Circulating immune complexes in patients with acute infectious hepatitis

We studied the content of circulating immune complexes in the blood serum of patients with acute infectious hepatitis in the dynamics of the disease, depending on the form of the severity of the process. The study was carried out according to a modified method in the precipitation reaction with polyethylene glycol (PEG reaction). The results were expressed in μg / ml of aggregated gamma globulin. 151 patients with acute infectious hepatitis of the icteric form, mild and moderate (age of patients - from 16 to 30 years) were under observation. The first studies in all patients were carried out on the 1-6th day from the onset of jaundice, in the period of the further course of the disease, before discharge from the hospital and one month after it. The diagnosis of infectious hepatitis was made on the basis of generally accepted criteria using liver function tests. The Australian antigen was not detected in the patients' blood. Patients were treated according to the severity of infectious hepatitis. None of the patients we observed were prescribed glucocorticosteroids.