Biochemical and histochemical assessment of iron balance in patients with iron deficiency anemia

The study of iron metabolism in 30 patients with iron deficiency anemia treated with ferbitol. In patients who did not have increased blood loss, after treatment with ferbitol, the biochemical parameters of iron metabolism and the number of sideroblasts normalized; an iron-containing pigment was found in the reticular cells of the bone marrow. In patients with chronic posthemorrhagic anemia, with satisfactory biochemical parameters and a sufficient number of sideroblasts, the iron-containing pigment was absent in the reticular cells. The most accurate information on the usefulness of remission in patients with iron deficiency anemia, including the restoration of iron stores, was provided by histochemical determination of ferritin in the reticular cells of the bone marrow stroma.