The effect of vitamin B15 (pangamic acid) on clinical symptoms and humoral disorders in coronary atherosclerosis

Vitamin B15 (pangamic acid) by chemical structure is an ester compound of gluconic acid with methylated glucin - dimethylglucin. Pangamic acid contains several methyl groups that are labile. According to Tsamp (1958), it is mainly methyl groups that determine the biological activity of vitamin Bis. He believes that the more methyl groups it contains, the higher the activity of the drug. Pangamic acid, due to the lability of its methyl groups, is a good donor of these groups (Beard and Wofford, 1956, Maniantini, 1959) Labile methyl groups are easily precipitated, and remethylation serves to activate oxidative processes and cellular respiration.