Secretory function of the salivary glands and the psychological factor: a randomized clinical study

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Abstract

BACKGROUND: It is widely believed that xerostomia may be caused by emotional tension, anxious anticipation, and stress.

AIM: This work aimed to investigate the influence of psychological factors on the secretory function of the parotid glands.

METHODS: A two-stage controlled longitudinal sialometry was performed in 75 patients with sialadenosis and sialadenitis accompanied by xerostomia. Saliva from the parotid ducts was collected simultaneously using a Lashley capsule and a polyethylene catheter. After one week, the collection methods were alternated. In 71 patients, psychological personality type was determined; salivary cortisol levels were measured in 51 cases before stage 1 and in 50 cases before stage 2 of the study. The secretory function of the parotid glands obtained using different saliva collection methods (Lashley capsule and polyethylene catheter), the distribution of introverts, ambiverts, and extroverts determined by questionnaire, and morning salivary cortisol levels measured at the INVITRO laboratory were compared during the controlled longitudinal sialometry. Statistical analysis was performed using methods of variational statistics. Arithmetic means and their standard errors were calculated (M ± m). Significance of differences was assessed using Student’s t-test. Differences were considered significant at p ≤ 0.05.

RESULTS: When assessed using the Lashley capsule, parotid gland secretory function (n = 75) was normal in 54.0% of cases, showed hyposalivation in 28.0% of cases, and asialia in 18.0% of cases. When using the catheter, the corresponding values were 39.3%, 42.0%, and 18.7%, respectively. Hyposalivation was detected notably more frequently when the catheter was used compared with the Lashley capsule (t = 2.5698). Among the patients (n = 71), introverts accounted for 53.5% (t = 8.0867; p = 0.001), ambiverts for 45.1% (t = 7.4103; p = 0.001), and extroverts for 1.4%. Salivary cortisol levels before sialometry were within the normal range in all cases (100.0%); no changes were observed between the two study stages (t = 1.1239; t = 1.1076).

CONCLUSION: Introverts and ambiverts are more predisposed to xerostomia than extroverts.

About the authors

Alexander V. Shchipskiy

Russian University of Medicine

Author for correspondence.
Email: Sialocenter@mail.ru
ORCID iD: 0000-0002-2851-0171
SPIN-code: 4263-8215

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Moscow

Marina M. Kalimatova

Russian University of Medicine

Email: dockalimatova@mail.ru
ORCID iD: 0000-0002-0935-8936

Graduate Student, Depart. of Maxillofacial Surgery and Traumatology

Russian Federation, Moscow

Pavel N. Mukhin

Russian University of Medicine

Email: panistom@mail.ru
ORCID iD: 0000-0002-8311-5529

MD, Cand. Sci. (Medicine). Assistant Lecturer, Depart. of Maxillofacial Surgery and Traumatology

Russian Federation, Moscow

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