Modern applications of 3D technologies for the treatment of bone tissue defects
- Authors: Bragina S.V.1, Bokareva K.O.1, Epifantsev G.O.1, Polyakova I.A.1
-
Affiliations:
- Northern State Medical University
- Issue: Vol 106, No 2 (2025)
- Pages: 235-242
- Section: Reviews
- URL: https://ogarev-online.ru/kazanmedj/article/view/292222
- DOI: https://doi.org/10.17816/KMJ641819
- ID: 292222
Cite item
Abstract
The use of 3D technologies offers more precise planning of surgical procedures in complex cases of localized bone tissue deficiency, allowing adaptation to individual anatomical features, improved outcomes, reduced risk of complications, and faster postoperative recovery. To analyze the current capabilities of three-dimensional printing in the surgical management of pelvic and hip bone defects, we reviewed scientific literature available in open-access databases including PubMed, eLibrary.Ru, Scopus, and Dimensions, with a search depth of up to 10 years. This review highlights major trends and advances in the medical application of 3D technologies aimed at reducing perioperative risks and improving patients’ quality of life in the context of bone tissue defects. Particular focus is placed on revision hip arthroplasty and pelvic oncologic conditions, where modern additive manufacturing technologies can enhance treatment quality and surgical outcomes. The methodology of 3D scanning for designing patient-specific implants is described. The review also demonstrates current and promising applications of 3D printing in clinical practice. Modern 3D technologies, particularly additive manufacturing, play an important role in improving surgical outcomes for skeletal deficiencies by enabling personalized treatment, expediting recovery, and improving patient prognosis. Emerging directions significantly expand the range of available reconstructive procedures, reduce the risk of complications, and ultimately improve patient quality of life and surgical efficiency.
Full Text
##article.viewOnOriginalSite##About the authors
Svetlana V. Bragina
Northern State Medical University
Author for correspondence.
Email: svetabragina69@mail.ru
ORCID iD: 0000-0002-0900-4572
SPIN-code: 5490-9821
Cand. Sci. (Med.), Assistant Prof., Head of Depart., Depart. of Traumatology, Orthopedics and Military Surgery
Russian Federation, 51 Troitsky ave, Arkhangelsk,163069Karina O. Bokareva
Northern State Medical University
Email: bokarkar@yandex.ru
ORCID iD: 0009-0001-6924-3233
SPIN-code: 6406-1075
6th year stud., Depart. of General Medicine
Russian Federation, 51 Troitsky ave, Arkhangelsk,163069Gleb O. Epifantsev
Northern State Medical University
Email: rozgles@yandex.ru
ORCID iD: 0009-0002-3881-8417
SPIN-code: 2760-1987
6th year stud., Depart. of General Medicine
Russian Federation, 51 Troitsky ave, Arkhangelsk,163069Irina A. Polyakova
Northern State Medical University
Email: pirinka51@gmail.com
ORCID iD: 0009-0001-1717-2752
SPIN-code: 9023-8516
6th year stud., Depart. of General Medicine
Russian Federation, 51 Troitsky ave, Arkhangelsk,163069References
- Nagibovich OA, Svistov DV, Peleshok SA, et al. Primenenie tehnologii 3D-pechati v medicine. Clinical Pathophysiology. 2017;23(3):14–22. EDN: XWJNKD
- Hull CW, inventor; 3D Systems Inc., assignee. Apparatus for Production of Three-Dimensional Objects by Stereolithography. United States patent US 4575330A. 08.08.1984. 11.03.1986.
- Agarwal P, Arora G, Panwar A, et al. Diverse Applications of Three-Dimensional Printing in Biomedical Engineering: A Review. 3D Print Addit Manuf. 2023;10(5):1140–1163. doi: 10.1089/3dp.2022.0281 EDN: CXZCRF
- Mendonça CJA, Guimarães RMDR, Pontim CE, et al. An Overview of 3D Anatomical Model Printing in Orthopedic Trauma Surgery. J Multidiscip Healthc. 2023;16(4):875–887. doi: 10.2147/JMDH.S386406 EDN: OSBUMU
- Woo SH, Sung MJ, Park KS, Yoon TR. Three-dimensional-printing Technology in Hip and Pelvic Surgery: Current Landscape. Hip Pelvis. 2020;32(1):1–10. doi: 10.5371/hp.2020.32.1.1 EDN: BDBDDJ
- Kavalerskii G, Murylev V, Rukin Ya, et al. 3D technologies for revision total hip arthroplasty. Vrach. 2016;2016(11):47–49. EDN: XBJKHJ
- Tack P, Victor J, Gemmel P, Annemans L. Do custom 3D-printed revision acetabular implants provide enough value to justify the additional costs? The health-economic comparison of a new porous 3D-printed hip implant for revision arthroplasty of Paprosky type 3B acetabular defects and its closest alternative. Orthop Traumatol Surg Res. 2021;107(1):1–10. doi: 10.1016/j.otsr.2020.03.012 EDN: UBCAXI
- Qu Z, Yue J, Song N, Li S. Innovations in 3D printed individualized bone prosthesis materials: revolutionizing orthopedic surgery: a review. Int J Surg. 2024;110(10):6748-6762. doi: 10.1097/JS9.0000000000001842
- Fang S, Wang Y, Xu P, et al. Three-dimensional-printed titanium implants for severe acetabular bone defects in revision hip arthroplasty: short- and mid-term results. Int Orthop. 2022;46(6):1289–1297. doi: 10.1007/s00264-022-05390-5 EDN: QNWXJG
- Ranzzi A, Lucena RL, Schwartsmann CR, et al. Comparative Study with and without the Use of 3D Prototyping of an Unconventional Technique in the Surgical Planning of Revision of Total Hip Arthroplasty. Rev Bras Ortop. 2021;57(5):884–890. doi: 10.1055/s-0041-1731659 EDN: NJMDCW
- Murylev VY, Kukovenko GA, Elizarov PM, et al. Comparative evaluation of custom-made components and standard implants for acetabular reconstruction in revision total hip arthroplasty. Traumatology and orthopedics of Russia. 2023;29(3):18–30. doi: 10.17816/2311-2905-2553 EDN: WTOGWU
- Min L, Li L, Hu X, et al. Application of modified Gibson combined with modified ilioinguinal approach in treatment of Enneking II+III pelvic malignant tumors with three-dimensional printed hemipelvic prosthesis replacement. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2022;36(7):796–803. doi: 10.7507/1002-1892.202203004
- Wu Y, Liu J, Kang L, et al. An overview of 3D printed metal implants in orthopedic applications: Present and future perspectives. Heliyon. 2023;9(7):e17718. doi: 10.1016/j.heliyon.2023.e17718 EDN: HXOLRE
- Yarikov AV, Gorbatov RO, Denisov AA, et al. Application of additive 3d printing technologies in neurosurgery, vertebrology and traumatology and orthopedics. Journal of clinical practice. 2021;12(1):90–104. doi: 10.17816/clinpract64944 EDN: BFYECO
- Zhang JW, Liu XL, Zeng YM, et al. Comparison of 3D Printing Rapid Prototyping Technology with Traditional Radiographs in Evaluating Acetabular Defects in Revision Hip Arthroplasty: A Prospective and Consecutive Study. Orthop Surg. 2021;13(6):1773–1780. doi: 10.1111/os.13108 EDN: WMQINP
- Wang W, Liu P, Zhang B, et al. Fused Deposition Modeling Printed PLA/Nano β-TCP Composite Bone Tissue Engineering Scaffolds for Promoting Osteogenic Induction Function. Int J Nanomedicine. 2023;18:5815–5830. doi: 10.2147/IJN.S416098 EDN: WVLCYD
- Zagorodniy NV, Chragyan GA, Kagramanov SV. Application of 3D modeling and prototyping in primary and revision acetabular arthroplasty. In: Spring Days of Orthopedics: abstracts of the International Congress, Moscow, March 01–02, 2019. Zagorodniy NV, editor. Moscow: Peoples’ Friendship University of Russia (RUDN); 2019. P. 79–81. (In Russ.) EDN: DNRPDX
- Meynen A, Vles G, Roussot M, et al. Advanced quantitative 3D imaging improves the reliability of the classification of acetabular defects. Arch Orthop Trauma Surg. 2023;143(3):1611–1617. doi: 10.1007/s00402-022-04372-x EDN: LENQLI
- Fu J, Ni M, Zhu F, et al. Reconstruction of Paprosky Type III Acetabular Defects by Three-Dimensional Printed Porous Augment: Techniques and Clinical Outcomes of 18 Consecutive Cases. Orthop Surg. 2022;14(5):1004–1010. doi: 10.1111/os.13250 EDN: VMDIGI
- Li Q, Chen X, Lin B, et al. Three-dimensional technology assisted trabecular metal cup and augments positioning in revision total hip arthroplasty with complex acetabular defects. J Orthop Surg Res. 2019;14(1):1–9. doi: 10.1186/s13018-019-1478-1 EDN: LWHTGX
- Xiao C, Zhang S, Gao Z, Tu C. Custom-made 3D-printed porous metal acetabular composite component in revision hip arthroplasty with Paprosky type III acetabular defects: A case report. Technol Health Care. 2023;31(1):283–291. doi: 10.3233/THC-212984 EDN: MGFGLO
- Wang J, Min L, Lu M, et al. Three-dimensional-printed custom-made hemipelvic endoprosthesis for the revision of the aseptic loosening and fracture of modular hemipelvic endoprosthesis: a pilot study. BMC Surg. 2021;21(1):1–10. doi: 10.1186/s12893-021-01257-5 EDN: OMZIRL
- Chinnasami H, Dey MK, Devireddy R. Three-Dimensional Scaffolds for Bone Tissue Engineering. Bioengineering. 2023;10(7):1–32. doi: 10.3390/bioengineering10070759 EDN: ITHZDP
- Okolie O, Stachurek I, Kandasubramanian B, Njuguna J. 3D Printing for Hip Implant Applications: A Review. Polymers. 2020;12(11):1–28. doi: 10.3390/polym12112682 EDN: IEFXFE
- Zhang BH, Fu J, Zhang GQ, et al. The reconstruction techniques and mid-term clinical outcomes of hip revision for acetabular bone defect after total hip arthroplasty. Zhonghua Wai Ke Za Zhi. 2024;62(9):836–846. doi: 10.3760/cma.j.cn112139-20240514-00243
- Hu X, Wen Y, Lu M, et al. Biomechanical and clinical outcomes of 3D-printed versus modular hemipelvic prostheses for limb-salvage reconstruction following periacetabular tumor resection: a mid-term retrospective cohort study. J Orthop Surg Res. 2024;19(1):1–17. doi: 10.1186/s13018-024-04697-w EDN: TLTXEF
- Henckel J, Holme TJ, Radford W, et al. 3D-printed Patient-specific Guides for Hip Arthroplasty. Journal of the American Academy of Orthopaedic Surgeons. 2018;26(16):342–348. doi: 10.5435/JAAOS-D-16-00719
- Liu X, Luo Y, He X, et al. Three-dimensional-printed hemi-pelvic prosthesis for revision of aseptic loosening or screw fracture of modular hemi-pelvic prosthesis. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023;37(10):1183–1189. doi: 10.7507/1002-1892.202306073
- Zheravin AA, Taranov PA, Krasil’nikov SE, et al. Implementation of innovative additive technologies in medical practice. Opinion Leader. 2021;46(5):32–36. (In Russ.) EDN: HDXFTJ
- Joviić MŠ, Vuletić F, Ribiić T, et al. Implementation of the three-dimensional printing technology in treatment of bone tumours: a case series. Int Orthop. 2021;45(4):1079–1085. doi: 10.1007/s00264-020-04787-4 EDN: AIKFYB
- Hu X, Lu M, Wang Y, et al. Advanced Pelvic Girdle Reconstruction with three dimensional-printed Custom Hemipelvic Endoprostheses following Pelvic Tumour Resection. Int Orthop. 2024;48(8):2217–2231. doi: 10.1007/s00264-024-06207-3 EDN: PZTFSX
- Li Z, Chen G, Xiang Y, et al. Treatment of massive iliac chondrosarcoma with personalized three-dimensional printed tantalum implant: a case report and literature review. J Int Med Res. 2020;48(10):1–10. doi: 10.1177/0300060520959508 EDN: ZBWCES
- Angelini A, Kotrych D, Trovarelli G, et al. Analysis of principles inspiring design of three-dimensional-printed custom-made prostheses in two referral centres. Int Orthop. 2020;44(5):829–837. doi: 10.1007/s00264-020-04523-y EDN: BKKPVQ
- Peng W, Zheng R, Wang H, Huang X. Reconstruction of Bony Defects after Tumor Resection with 3D-Printed Anatomically Conforming Pelvic Prostheses through a Novel Treatment Strategy. Biomed Res Int. 2020;2020(1):1–16. doi: 10.1155/2020/8513070 EDN: AXNWOA
- Wang J, Min L, Lu M, et al. What are the Complications of Three-dimensionally Printed, Custom-made, Integrative Hemipelvic Endoprostheses in Patients with Primary Malignancies Involving the Acetabulum, and What is the Function of These Patients? Clin Orthop Relat Res. 2020;478(11):2487–2501. doi: 10.1097/CORR.0000000000001297 EDN: HAPNGZ
- Agaev DK, Sushentsov EA, Sofronov DI, et al. The use of computer modeling and 3d-technologies in oncoorthopedia. Literature review. Bone and soft tissue sarcomas, tumors of the skin. 2019;11(4):5–16. EDN: NIPOJT (In Russ.).
- Aguado-Maestro I, Simón-Pérez C, García-Alonso M, et al. Clinical Applications of “In-Hospital” 3D Printing in Hip Surgery: A Systematic Narrative Review. J Clin Med. 2024;13(2):1–16. doi: 10.3390/jcm13020599 EDN: EWMWQT
- Lewandrowski KU, Vira S, Elfar JC, Lorio MP. Advancements in Custom 3D-Printed Titanium Interbody Spinal Fusion Cages and Their Relevance in Personalized Spine Care. J Pers Med. 2024;14(8):1–31. doi: 10.3390/jpm14080809 EDN: EWFBTP
- Lee JJ, Jacome FP, Hiltzik DM, et al. Evolution of Titanium Interbody Cages and Current Uses of 3D Printed Titanium in Spine Fusion Surgery. Curr Rev Musculoskelet Med. 2024. doi: 10.1007/s12178-024-09912-z EDN: VXAHBQ
- Qin H, Wei Y, Han J, et al. 3D printed bioceramic scaffolds: Adjusting pore dimension is beneficial for mandibular bone defects repair. J Tissue Eng Regen Med. 2022;16(4):409–421. doi: 10.1002/term.3287 EDN: TDFGGC
- Kotel’nikov GP, Kolsanov AV, Nikolaenko AN, et al. Application of 3D modeling and additive technologies in personalized medicine. Bone and soft tissue sarcomas and skin tumors. 2017;2017(1):20–26. (In Russ.)
- Shkrum AS, Katasonova GR. Trends in the use of additive technologies in various subject areas and in the medical field. Ural’skij medicinskij zhurnal. 2020;188(05):216–220. doi: 10.25694/URMJ.2020.05.38 EDN: NVQJGY
Supplementary files
