Clinical features of rosacea in combination with demodicosis

Aim. To study the features of the clinical course of rosacea in combination with demodicosis. Methods. The study included patients aged 19 to 59 years with rosacea (n=71), in whom Demodex mite were identified. Gender and age-comparable patients with rosacea and without demodicosis (n=68) were examined as comparison group. The disease duration in both groups ranged from 2-3 weeks to 7 years. Clinical examination, Demodex folliculorum identification were performed. Diagnostic criteria for clinical forms of rosacea were used for diagnosis and staging of the disease. Results. The pustular form of the disease was more prevalent in patients with rosacea, complicated by demodicosis. The combination of erythema with skin edema was found in all patients with a pustular form of the disease, bigger grouped skin rash elements having an infiltration bed were revealed in a greater degree. In patients with papular form of rosacea, complicated by demodicosis, skin rash elements were localized all over the face in 33.3% of cases, in comparison group similar rash was noted in 12.5% of cases. In patients with rosacea, complicated by demodicosis, most of the patients suffered relapses at least twice a year and more. In cases of rosacea without demodicosis relapses were significantly less frequent. Conclusion. In patients with rosacea, complicated by demodicosis more severe clinical course of the disease was observed with a prevalence of pustular forms and the greater skin area involved.

rosacea, demodicosis, clinical course, clinical forms of rosacea, relapse