50 years in search of the «longevity» gene
- Authors: Chugunova DN1, Oslopov VN1
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Affiliations:
- Kazan State Medical University, Russia
- Issue: Vol 93, No 6 (2012)
- Pages: 849-854
- Section: Lead article
- URL: https://ogarev-online.ru/kazanmedj/article/view/2090
- DOI: https://doi.org/10.17816/KMJ2090
- ID: 2090
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##article.viewOnOriginalSite##About the authors
D N Chugunova
Kazan State Medical University, Russia
Email: d0129@yandex.ru
V N Oslopov
Kazan State Medical University, Russia
References
- Анисимов В.Н. Молекулярные и физиологические механизмы старения. - СПб.: Наука, 2003. - 468 с.
- Глотов О.С., Баранов В.С. Генетический полиморфизм, мультифакториальные болезни и долголетие // Мед. генетика. - 2007. - Т. 6, №4. - С. 17-30.
- Макаров М.А., Ослопов В.Н. Результаты длительного наблюдения за динамикой заболеваемости первичной артериальной гипертензией в мужской когорте в зависимости от функционального состояния клеточных мембран // Практ. мед. - 2011. - №4. - С. 49-52.
- Малыгина Н.А., Костомарова И.В., Криводубская Т.Ю. и др. Анализ полиморфизма гена ангиотензин-превращающего фермента у больных ишемической болезнью сердца и гипертонией // Кардиология. - 2000. - №4. - С. 19-22.
- Постнов Ю.В., Орлов С.Н. Первичная гипертензия как патология клеточных мембран. - М.: Медицина, 1987. - 192 с.
- Хавинсон В.Х., Анисимов С.В., Малинин В.В., Анисимов В.Н. Пептидная регуляция генома и старение. - М.: изд-во РАМН, 2005. - 208 с.
- Andersen-Ranberg K. Healthy centenarians do not exist, but autonomous centenarians do: a population-based study of morbidity among Danish Centenarians // J. Am. Geriatr. Soc. - 2001. - Vol. 49. - P. 900-908.
- Anisimov S.V., Volkova M.V., Lenskaya L.V. Age-associated accumulation of the apolipoprotein C-III gene T-455C polymorphism C allele in a Russian population // J. Gerontol. A. Biol. Sci. Med. Sci. - 2001. - Vol. 56. - P. 27-32.
- Bathum L. No evidence for an association between extreme longevity and microsomal transfer protein polymorphisms in a longitudinal study of 1651 nonagenarians // Eur. J. Hum. Genet. - 2005. - Vol. 13. - P. 1154-1158.
- Bathum L. Association of mutations in the hemochromatosis gene with shorter life expectancy // Arch. Intern. Med. - 2001. - Vol. 16. - P. 2441-2444.
- Bathum L. Apolipoprotein E genotypes: relationship to cognitive functioning, cognitive decline, and survival in nonagenarians // J. Am. Geriatr. Soc. - 2006. - Vol. 54. - P. 654-658.
- Berzlanovich A.M. Do centenarians die healthy? An autopsy study // J. Gerontol. A. - 2005. - Vol. 60. - P. 862-865.
- Beutler E. Penetrance of 845G>A (C282Y) HFE hereditary haemochromatosis mutation in the USA // Lancet. - 2002. - Vol. 359. - P. 211-218.
- Blanche H., Cabanne L., Sahbatou M., Thomas G. A study of French centenarians: are ACE and APOE associated with longevity? // CR Acad. Sci. III. - 2001. - Vol. 324. - P. 129-135.
- Bonafe M. Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of lifespan control // J. Clin. Endocrinol. Metab. - 2003. - Vol. 88. - P. 3299-3304.
- Christiansen L. Modest implication of interleukin-6 promoter polymorphisms in longevity // Mech. Ageing. - 2004. - Vol. 125. - P. 391-395.
- Coppin H. Longevity and carrying the C282Y mutation for haemochromatosis on the HFE gene: case control study of 492 French centenarians // BMJ. - 2003. - Vol. 327. - P. 132-133.
- De Maat M.P. Genetic influence on inflammation variables in the elderly // Arterioscler. Thromb. Vasc. Biol. - 2004. - Vol. 24. - P. 2168-2173.
- De Craen A.J. Heritability estimates of innate immunity: an extended twin study // Genes Immun. - 2005. - Vol. 6. - P. 167-170.
- Finch C.E., Ruvkun G. Genetics of aging // Annu. Rev. Genomics. Hum. Genet. - 2001. - Vol. 2. - P. 435-462.
- Finch C.E., Crimmins E.M. Inflammatory exposure and historical changes in human life-spans // Science. - 2004. - Vol. 305. - P. 1736-1739.
- Francheschi C. Inflamm-aging. An evolutionary perspective on immunosenescence // Ann. NY Acad. Sci. - 2000. - Vol. 908. - P. 244-254.
- Flachsbart F. Association of FOXO3A variation with human longevity confirmed in German centenarians // Proc. Natl. Acad. Sci. USA. - 2009. - Vol. 106, N 8. - P. 2700-2705.
- Frederiksen H. Angiotensin I-converting enzyme (ACE) gene polymorphism in relation to physical performance, cognition and survival-a follow-up study of elderly Danish twins // Ann. Epidemiol. - 2003. - Vol. 13. - P. 57-65.
- Garasto S., Rose G., Derango F. et al. The study of APOA1, APOC3 and APOA4 variability in healthy ageing people reveals another paradox in the oldest old subjects // Ann. Human Gen. - 2003. - Vol. 67. - P. 54-62.
- Geesaman B.J. Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan // Proc. Natl. Acad. Sci. USA. - 2003. - Vol. 100. - P. 14115-14120.
- Gerdes L.U. Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: apolipoprotein E gene is a «frailty gene», not a «longevity gene» // Genet. Epidemiol. - 2000. - Vol. 19. - P. 202-210.
- Gudmundsson G. Inheritance of human longevity in Iceland // Eur. J. Hum. Genet. - 2000. - Vol. 8. - P. 743-749.
- Hjelmborg J.V. Genetic influence on human lifespan and longevity // Human Genet. - 2006. - Vol. 119. - P. 312-321.
- Humphries S.E., Luong L.A., Ogg M.S. et al. The interleukin-6 -174G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men // Eur. Heart J. - 2001. - Vol. 22. - P. 2243-2252.
- Hurme M., Lehtimaki T., Jylha M. et al. Interleukin-6 -174G/C polymorphism and longevity: a follow-up study // Mech. Ageing. - 2005. - Vol. 26. - P. 417-418.
- Johnson T.E. Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging // Science. - 1990. - Vol. 249, N 4971. - P. 908-912.
- Kenyon С., Dorman J.B., Albinder B., Shroyer T. The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans // Genetics. - 1995. - Vol. 4. - P. 1399-1406.
- Kerber R.A. Familial excess longevity in Utah genealogies // J. Gerontol. A. - 2001. - Vol. 56. - P. 130-139.
- Klass M.R. A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results // Mech. Ageing. - 1983. - Vol. 22. - P. 279-286.
- Kleindorp R., Flachsbart F., Puca A.A. et al. Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans // Aging Cell. - 2011. - Vol. 4. - P. 622-628.
- Lio D. Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-α -308 promoter SNP // J. Med. Genet. - 2003. - Vol. 40. - P. 296-299.
- Luft F.C. Bad genes, good people, association, linkage, longevity and the prevention of cardiovascular disease // Clin. Exp. Pharmacol. Physiol. - 1999. - Vol. 26. - P. 576-579.
- Medawar P.B., Lewis H.K. An unsolved problem of biology. In: Uniqueness of the Individual // New York Basic books, 1952. - 284 p.
- Nauck M. The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction // J. Mol. Med. - 2002. - Vol. 80. - P. 507-513.
- Nebel A. No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans // Proc. Natl. Acad. Sci. USA. - 2005. - Vol. 102. - P. 7906-7909.
- Perls T., Kunkel L.M., Puca A.A. The genetics of exceptional human longevity // J. of Molec. Neur. - 2002. - Vol. 19. - P. 233-238.
- Schachter F. Genetic associations with human longevity at the APOE and ACE loci // Nat. Genet. - 1994. - Vol. 6. - P. 29-32.
- Schoenmaker M. Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study // Eur. J. Hum. Genet. - 2005. - Vol. 14. - P. 79-84.
- Silve M.H., Jilinskaia E., Perls T.T. Cognitive functional status of age-confirmed centenarians in a population-based study // J. Gerontol. B. Psychol. Sci. Soc. Sci. - 2001. - N 56. - P. 134-140.
- Skytthe A. Longevity studies in Genom EU twin // Twin Res. - 2003. - Vol. 6. - P. 448-454.
- Van Heemst D. Reduced insulin/IGF-1 signalling and human longevity // Aging Cell. - 2005. - Vol. 4. - P. 79-85.
- Willcox B.J. FOXO3A genotype is strongly associated with human longevity // Proc. Natl. Acad. Sci. USA. - 2008. - Vol. 105, N 37. - P. 13 987-13 992.
- Williams G.C. Pleiotropy, natural selection and the evolution of senescence // Evolution. - 1957. - Vol. 11. - P. 398-411.
- Weindruch R., Walford R.L. The retardation of aging and disease by dietary restriction on the transcriptional profile of skeletal muscle from rhesus monkeys // Proc. Nat. Acad. Sci. - 2001. - Vol. 98. - P. 5093-5098.
- World health statistics, 2010. World Health Organization. - Geneva, 2010. - 177 p.
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