Terlipressin as the element of medicamentous technique redicing blood loss in proximal ­resection of pancreatic head in a patient with extrahepatic form of portal hypertension as the outcome of chronic pancreatitis

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Abstract

The article presents a case of the use of medicamentous technique redicing blood loss with terlipressin — a long-acting synthetic analogue of antidiuretic hormone. This pharmaceutical drug causes constrictin of arterioles, veins and venules, which leads to the reduction of blood flow in the visceral organs and pressure reduction in the portal system. In our federal institution of healthcare, a patient with chronic pancreatitis complicated by segmentary portal hypertension and portal cavernoma underwent proximal resection of pancreatic head by C. Fray, placing of a longitudinal pancreatojejunoanastomosis and azigoportal disconnection. The description of this case is aimed at drawing attention to relatively new and developing methods of medicamentous technique redicing blood loss, which in combination with surgical methods allows reducing perioperative blood loss in upper abdominal surgeries.

About the authors

E A Borodenko

Clinics of Samara State Medical University

Author for correspondence.
Email: kate1304@yandex.ru
Russian Federation, Samara, Russia

A D Gureev

Clinics of Samara State Medical University; Samara State Medical University

Email: kate1304@yandex.ru
Russian Federation, Samara, Russia; Samara, Russia

I V Kolesnik

Clinics of Samara State Medical University

Email: kate1304@yandex.ru
Russian Federation, Samara, Russia

I G Trukhanova

Clinics of Samara State Medical University; Samara State Medical University

Email: kate1304@yandex.ru
Russian Federation, Samara, Russia; Samara, Russia

References

  1. Vachev A.N., Trukhanova I.G., Gureev A.D. Method for prevention of diffuse intra- and postoperative blood loss during reconstruction of the aortoiliac segment. Patent for invention RF №2540923. Bulletin №4 issued on 10.02.2015. (In Russ.)
  2. Kolsanov A.V., Katorkin S.E., Zel’ter P.M. et al. Virtual planning in abdominal surgery: experience of the use of surgery of the liver, spleen and pancreas. Klinicheskaya i eksperimentalʹnaya khirurgiya. Zhurnal imeni akademika B.V. Petrov­skogo. 2017; (1): 31–36. (In Russ.)
  3. Kuznetsov N.A. Modern technologies for the treatment of acute blood loss. Consilium Medicum. 2003; (6): 347–357. (In Russ.)
  4. Levacher S., Letoumelin P., Pateron D. et al. Early administration of terlipressin plus glyceryl trinitrate to control active upper gastrointestinal bleeding in cirrhotic patients. Lancet. 1995; 346 (8979): 865–868. doi: 10.1016/s0140-6736(95)92708-5.
  5. Pasechnik I.N., Salʹnikov P.S. Bleeding from the varicose veins of the esophagus and stomach in liver cirrhosis. Khirurgiya. 2013; (8): 76–80. (In Russ.)
  6. Pasechnik I.N., Skobelev E.I. Blood saving technologies in surgery: new opportunities. Effektivnaya farmakoterapiya. 2015; (1): 36–40. (In Russ.)

Supplementary files

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1. JATS XML
2. Рис. 1. Компьютерная томограмма органов брюшной ­полости

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3. Рис. 2. 3D-реконструкция портальной каверномы по данным компьютерной томографии

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4. Рис. 3. Схема операции: 1 — варикозно расширенные вены желудка; 2 — поджелудочная железа; 3 — дренажи к панкреатоеюноанастомозу; 4 — дренаж в подпечёночное пространство; 5 — панкреатоеюноанастомоз; 6 — межкишечный анастомоз (Roux-en-Y)

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© 2020 Borodenko E.A., Gureev A.D., Kolesnik I.V., Trukhanova I.G.

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