Treatment endometrium cancer with preserving fertility - analysis of literature data and own studies

Spontaneous and distant results were analyzed concerning hormonal treatment of 47 initial patients of reproductive age with endometrium cancer (EC). The cure in the prof. N.N.Petrov scientific-research institute was performed from 1975 with purpose of preseiving fertility without operation. In addition, literature data concerning analogical treatment of 36 patients were analyzed. Summary of all data concerning 83 patients EC without invasion in myometrium show about 80% patients were receptive to hormonotherapy and 61% had the full regression of endometrium tumor. The pregnancy occurs in 20% of patients, childbirth happen in 12% of patients. Relapses of illness were revealed in almost one half of 66 patients (48%) after the full regression of initial EC. Unique results obtained in the prof. N.N. Petrov scientific-research institute oncological department are explained by large number of observations and long monitoring patients. These data analysis allowed to define indications and conditions for use of such cure EC method: only inpatients with minimal high-differentiated Aden carcinoma and in specialized clinics. This method does not exclude any timely surgery cure component in case of relapse and together with it permits to realize the reproductive function.