Email this article The case of abdominal delivery in acute heteroimmune drug indused thrombocytopenia
- Authors: Shirokov D.M.1,2,3, Bolotskikh V.M.1, Dzhanashia M.M.1, Eremeeva D.R.1, Korostelev Y.M.1,2, Vartanova I.V.1,2, Blinov A.E.2
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Affiliations:
- Ott Research Institute of Obstetrics, Gynecology and Reproductology
- Saint Petersburg Pavlov State Medical University
- Kirov Military Medical Academy
- Issue: Vol 66, No 4 (2017)
- Pages: 79-83
- Section: Articles
- URL: https://ogarev-online.ru/jowd/article/view/6922
- DOI: https://doi.org/10.17816/JOWD66479-83
- ID: 6922
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Abstract
The secondary gravida pregnant patient with uterine scar after previous cesarean section was treated with parenteral methamizol sodium due to renal colic and acute thrombocytopenia suddenly occurred. There were supposed that this condition had been drugs induced heteroimmune thrombocytopenia. The indications for planned cesarean section were breech presentation of large fetus in patient with uterine scar. However, uterine contractions appeared in 38/39 weeks and it was decided to deliver the patient urgently after appropriate preparing. The treating of severe thrombocytopenia was substitutive — thromboconcentrate and plasma transfusion and pathogenetic — using of dexamethasone and human immunoglobulin. After transfusion of one dose of thromboconcentrate and two doses of plasma the level of thrombocytes had reached of 21 × 109/л and it was decided to start cesarean section which was performed successfully in conditions of total combined anesthesia with tracheal intubation and pulmonary ventilation. The recovery of thrombocytes quantity occurred in postoperative period with continuing using of steroid therapy.
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##article.viewOnOriginalSite##About the authors
Dmitriy M. Shirokov
Ott Research Institute of Obstetrics, Gynecology and Reproductology; Saint Petersburg Pavlov State Medical University; Kirov Military Medical Academy
Author for correspondence.
Email: dm_shirokov@interzet.ru
MD. Head of the of Anesthesiology department
Russian Federation, 3, Mendeleevskaya line, Saint Petersburg, 199034; 6/9, Lva Tolstogo street, St. Petersburg, 197089; 6G, Akademika Lebedeva street, Saint-Petersburg, 194044Vyacheslav M. Bolotskikh
Ott Research Institute of Obstetrics, Gynecology and Reproductology
Email: docgin@yandex.ru
PhD Deputy director for medical work
Russian Federation, 3, Mendeleevskaya line, Saint Petersburg, 199034Manana M. Dzhanashia
Ott Research Institute of Obstetrics, Gynecology and Reproductology
Email: manana.ott@yandex.ru
MD. Head of Pregnancy Pathology Department No 2
Russian Federation, 3, Mendeleevskaya line, Saint Petersburg, 199034Dina R. Eremeeva
Ott Research Institute of Obstetrics, Gynecology and Reproductology
Email: dina-bikmullina@yandex.ru
MD. obstetrician-gynecologist of Pregnancy Pathology Department No 2
Russian Federation, 3, Mendeleevskaya line, Saint Petersburg, 199034Yury M. Korostelev
Ott Research Institute of Obstetrics, Gynecology and Reproductology; Saint Petersburg Pavlov State Medical University
Email: juko_71@mail.ru
MD. anesthesiologist
3, Mendeleevskaya line, Saint Petersburg, 199034; 6/9, Lva Tolstogo street, St. Petersburg, 197089Irina V. Vartanova
Ott Research Institute of Obstetrics, Gynecology and Reproductology; Saint Petersburg Pavlov State Medical University
Email: ivartanova@mail.ru
MD. anesthesiologist
Russian Federation, 3, Mendeleevskaya line, Saint Petersburg, 199034; 6/9, Lva Tolstogo street, St. Petersburg, 197089Aleksey E. Blinov
Saint Petersburg Pavlov State Medical University
Email: 79046408390@yandex.ru
internist anesthesiologist
Russian Federation, 6/9, Lva Tolstogo street, St. Petersburg, 197089References
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