Fetal brain venous return in complicated pregnancy

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Abstract

Objective. To estimate the fetal brain venous return in the complicated pregnancy.

Methods. Blood flow waveforms (BFW) in jugular vein (JV) were recorded in 162 fetuses from 13 to 40 weeks of normal gestation and in 63 growth restricted fetuses. Peak velocity in ventricular systole (S), peak velocity in early diastole which corresponds to passive ventricular filling (D), peak velocity in atria contraction with active ventricular filling (A), mean velocity (TAV) were measured and pulsatility index (PIV=S-A/TAV), systolic to diastolic ratio (S/D) were calculated.

Results. S, D, A, TAV in growth restricted fetuses were significantly greater and PIV, S/D were significantly lower than in normal fetuses after 36 weeks of gestation.

Conclusions. The results demonstrate that there are neuroprotective reactions of fetal cerebral venous blood flow after 36 weeks of gestation.

About the authors

Eduard K. Ailamazyan

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com

Academician of the Russian Academy of Medical Sciences, Honored Scientist of the Russian Federation, Professor, Director

Russian Federation, Saint Petersburg

Albert A. Polyanin

State Medical University named after acad. I.P. Pavlova

Email: info@eco-vector.com

Professor

Russian Federation, Saint Petersburg

Igor Y. Kogan

Saint Petersburg State University

Author for correspondence.
Email: info@eco-vector.com

Professor, Faculty of Medicine

Russian Federation, Saint Petersburg

References

Supplementary files

Supplementary Files
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2. Fig. 1. Longitudinal section of the upper half of the body of the fetus

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3. Fig. 2. Blood flow velocity curve in the inferior vena cava in the fetus

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4. Fig. 3. Doppler ultrasonography of blood flow in the internal jugular vein in a fetus developing during an uncomplicated pregnancy (30 weeks

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5. Fig. 4. Doppler blood flow in the internal jugular vein in the fetus with placental insufficiency (30 weeks

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6. Fig. 5. Dynamics of changes in the pulsation index of veins (PIV) in the internal jugular vein of the fetus with a normally developing pregnancy (N) and with placental insufficiency (PN)

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7. Fig. 6. The value of the pulsation index (PIV) in the internal jugular vein at 28-32 weeks of gestation

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8. Fig. 7. The value of the pulsation index (PIV) in the internal jugular vein at 33-36 weeks of pregnancy

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9. Fig. 8. The value of the pulsation index (PIV) in the internal jugular vein at 37-40 weeks of gestation

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