Current trends in the treatment of chronic placental insufficiency
- 作者: Novitskaya E.V.1, Bolotskikh V.M.1,2,3, Polyakova V.O.1, Kvetnoy I.M.1
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隶属关系:
- Saint Petersburg State University
- Saint Petersburg State Pediatric Medical University
- Maternity Hospital No. 9
- 期: 卷 69, 编号 1 (2020)
- 页面: 45-52
- 栏目: Original study articles
- URL: https://ogarev-online.ru/jowd/article/view/12634
- DOI: https://doi.org/10.17816/JOWD69145-52
- ID: 12634
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详细
According to literature, intrauterine growth retardation complicates about 5% of pregnancies and is usually caused by chronic placental insufficiency. This article reviews literature data on modern views on the issue. Special attention is paid to the role of melatonin in chronic placental insufficiency and intrauterine growth. Examples of experimental studies demonstrate successful pregnancy course and functional fetal development in animals with melatonin treatment. The data obtained by other researchers on the effect of melatonin on pregnancy, in particular, on chronic placental insufficiency in women, are analyzed. Also in this review, we suggest that melatonin, which is a powerful antioxidant, can reduce morbidity and mortality associated with intrauterine growth retardation.
作者简介
Ekaterina Novitskaya
Saint Petersburg State University
编辑信件的主要联系方式.
Email: keatnovitskay@rambler.ru
MD, Post-Graduate Student. The Department of Obstetrics, Gynecology, and Reproductive Sciences, Medical Faculty
俄罗斯联邦, Saint PetersburgVyacheslav Bolotskikh
Saint Petersburg State University; Saint Petersburg State Pediatric Medical University; Maternity Hospital No. 9
Email: iagmail@ott.ru
ORCID iD: 0000-0001-9846-0408
SPIN 代码: 3143-5405
MD, PhD, DSci (Medicine), Associate Professor. The Department of Obstetrics, Gynecology, and Reproductive Sciences, Medical Faculty; Professor. The Department of Obstetrics and Gynecology with Pediatric Gynecology Course; Head Physician
俄罗斯联邦, Saint PetersburgVictoria Polyakova
Saint Petersburg State University
Email: vopol@yandex.ru
ORCID iD: 0000-0001-8682-9909
SPIN 代码: 5581-5413
PhD, DSci (Biology), Professor, Professor of the Russian Academy of Sciences. The Department of Physiology, Medical Faculty
俄罗斯联邦, Saint PetersburgIgor Kvetnoy
Saint Petersburg State University
Email: igor.kvetnoy@yandex.ru
ORCID iD: 0000-0001-7302-5581
SPIN 代码: 7023-1838
MD, PhD, DSci (Medicine), Professor, Honored Scientist of the Russian Federation. The Department of Pathology, Medical Faculty
俄罗斯联邦, Saint Petersburg参考
- Андриевская И.А., Ишутина Н.А., Довжикова И.В. Плацентарная недостаточность: учебное пособие. – Благовещенск, 2017. – 43 c. [Andriyevskaya IA, Ishuchtina NA, Dovzhikova IV. Platsentarnaya nedostatochnost’: uchebnoye posobiye. Blagoveshchensk; 2017. 43 р. (In Russ.)]
- Проданова Е.В., Рогожина И.Е., Чехонацкая М.Л., Гришаева Л.А. Сравнительная допплерометрическая оценка эффективности терапии беременных с фетоплацентарной недостаточностью // Российский вестник акушера-гинеколога. – 2011. – Т. 11. – № 2. – С. 79−82. [Prodanova EV, Rogozhina IE, Chekhonatskaia ML, Grishaeva LA. Comparative Doppler evaluation of the efficiency of therapy in pregnant women with fetoplacental insufficiency. Rossiiskii vestnik akushera-ginekologa. 2011;11(2):79-82. (In Russ.)]
- Стрижаков А.Н., Тимохина Т.Ф., Баев О.Р. Фетоплацентарная недостаточность: патогенез, диагностика, лечение // Вопросы гинекологии, акушерства и перинатологии. – 2003. – Т. 2. – № 2. – С. 53–63. [Strizhakov AN, Timokhina TF, Baev OR. Fetoplacental insufficiency: pathogenesis, diagnostics, treatment. Problems of gynecology, obstetrics, and perinatology. 2003;2(2):53-63. (In Russ.)]
- Доброхотова Ю.Э., Джохадзе Л.С., Кузнецов П.А., Козлов П.В. Плацентарная недостаточность. Современный взгляд. – М.: ГЭОТАР-Медиа, 2019. – 59 c. [Dobrokhotova YuE, Dzhokhadze LS, Kuznetsov PA, Kozlov PV. Platsentarnaya nedostatochnost’. Sovremennyy vzglyad. Moscow: GEOTAR-Media; 2019. 59 р. (In Russ.)]
- Липатов И.С., Тезиков Ю.В., Линева О.И., и др. Патогенетические механизмы формирования плацентарной недостаточности и преэклампсии // Акушерство и гинекология. – 2017. – № 9. – C. 64−71. [Lipatov IS, Tezikov YV, Lineva OI, et al. Pathogenetic mechanisms of placental insufficiency and preeclampsia. Obstetrics and gynecology. 2017;(9):64-71. (In Russ.)]. https://doi.org/10.18565/aig.2017.9.64-71.
- Авруцкая В.В., Кулаков В.И., Радзинский В.Е., и др. Акушерство: национальное руководство / под ред. Э.К. Айламазяна и др. – М.: ГЭОТАР-Медиа, 2013. – 1197 с. [Avrutskaya VV, Kulakov VI, Radzinskiy VE, et al. Akusherstvo: natsional’noye rukovodstvo. Ed. by E.K. Aylamazyan, et al. Moscow: GEOTAR-Media; 2013. 1197 р. (In Russ.)]
- Аржанова О.Н., Кошелев Н.Г., Ковалева Т.Г., и др. Плацентарная недостаточность: диагностика и лечение: учебное пособие. – СПб.: Нордмед-Издат, 2000. – 32 c. [Arzhanova ON, Koshelev NG, Kovaleva TG, et al. Platsentarnaya nedostatochnost’: diagnostika i lecheniye. Uchebnoye posobiye. Saint Petersburg: Nordmed-Izdat; 2000. 32 р. (In Russ.)]
- Miller SL, Yawno T, Alers NO, et al. Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction. J Pineal Res. 2014;56(3):283-294. https://doi.org/10.1111/jpi.12121.
- Sagrillo-Fagundes L, Soliman A, Vaillancourt C. Maternal and placental melatonin: actions and implication for successful pregnancies. Minerva Ginecol. 2014;66(3):251-266.
- Князькин И.В., Кветной И.М., Зезолин П.Н., Филиппов С.В. Нейроиммуноэндокринология мужской половой системы, плаценты и эндометрия. – СПб.: Знание, 2007. – 192 c. (Научная серия: Молекулярная нейроиммуноэндокринология). [Knyaz’kin IV, Kvetnoi IM, Zezolin PN, Filippov SV. Neiroimmunoendokrinologiya muzhskoi polovoi sistemy, platsenty i endometriya. Saint Petersburg: Znanie; 2007. 192 р. (Scientific series: Molekulyarnaya neyroimmunoendokrinologiya). (In Russ.)]
- Sadowsky DW, Yellon S, Mitchell MS, Nathaniesz PW. Lack of effect of melatonin on myometrial electromyographic activity in the pregnant sheep at 138-142 days gestation (term = 147 days gestation). Endocrinology. 1991;128(4):1812-1818. https://doi.org/10.1210/endo-128-4-1812.
- Nakamura Y, Tamura H, Kashida S, et al. Changes of serum melatonin level and its relationship to feto-placental unit during pregnancy. J Pineal Res. 2001;30(1):29-33. https://doi.org/10.1034/j.1600-079x.2001.300104.x.
- Анисимов В.Н., Анисимов С.В., Арушанян Э.Б., и др. Мелатонин в норме и патологии / под ред. Ф.И. Комарова и др. – М.: Медпрактика-М, 2004. – 307 с. [Anisimov VN, Anisimov SV, Arushanyan EB, et al. Melatonin v norme i patologii. Ed. by F.I. Komarov. Moscow: Medpraktika-M; 2004. 307 р. (In Russ.)]
- Кветная Т.В., Князькин И.В., Кветной И.М. Мелатонин – нейроиммуноэндокринный маркер возрастной патологии. – СПб.: ДЕАН, 2005. – 142 с. (Научная серия: Молекулярная нейроиммуноэндокринология). [Kvetnaya TV, Knyaz’kin IV, Kvetnoi IM. Melatonin – neyroimmunoendokrinnyy marker vozrastnoy patologii. Saint Petersburg: DEAN; 2005. 142 р. (Scientific series: Molekulyarnaya neyroimmunoendokrinologiya). (In Russ.)]
- Reiter RJ, Tan DX, Korkmaz A, Rosales-Corral SA. Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology. Hum Reprod Update. 2014;20(2):293-307. https://doi.org/10.1093/humupd/dmt054.
- Ireland KE, Maloyan A, Myatt L. Melatonin improves mitochondrial respiration in syncytiotrophoblasts from placentas of obese women. Reproductive Sciences. 2018;25(1):120-130. https://doi.org/10.1177/1933719117704908.
- Айламазян Э.А., Евсюкова И.И., Кветной И.М. Мелатонин: беременность и роды // Журнал акушерства и женских болезней. – 2014. – Т. 63. – № 2. – C. 67−77. [Aylamazyan EK, Evsyukova II, Kvetnoy IM. Melatonin: pregnancy and labor. Journal of obstetrics and women’s diseases. 2014;63(2):67-77. (In Russ.)]
- Hobson SR, Gurusinghe S, Lim R, et al. Melatonin improves endothelial function in vitro and prolongs pregnancy in women with early-onset preeclampsia. J Pineal Res. 2018;65(3):e12508. https://doi.org/10.1111/jpi.12508.
- Sagrillo-Fagundes L, Clabault H, Laurent L, et al. Human primary trophoblast cell culture model to study the protective effects of melatonin against hypoxia/reoxygenation-induced disruption. J Vis Exp. 2016;(113):e54228. https://doi.org/10.3791/54228.
- Barchas J, Dacosta F, Spector S. Acute pharmacology of melatonin. Nature. 1967;214:919-920. https://doi.org/10.1038/ 214919a0.
- Valenzuela FJ, Vera J, Venegas C, et al. Circadian system and melatonin hormone: risk factors for complications during pregnancy, obstetrics and gynecology international. Obstet Gynecol Int. 2015;2015:825802. https://doi.org/10.1155/2015/825802.
- Reiter RJ, Tan DX, Korkmaz A, Rosales-Corral SA. Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology. Hum Reprod Update. 2014;20(2):293-307. https://doi.org/10.1093/humupd/dmt054.
- Mendez N, Abarzua-Catalan L, Vilches N, et al. Timed maternal melatonin treatment reverses circadian disruption of the fetal adrenal clock imposed by exposure to constant light. PLoS ONE. 2012;7(8):e42713. https://doi.org/10.1371/journal.pone.0042713.
- Voiculescu SE, Zygouropoulos N, Zahiu CD, Zagrean AM. Role of melatonin in embryo fetal development. J Med Life. 2014;7(4):488-492.
- Sousa Coelho ID, Lapa Neto CJ, Souza TG, et al. Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy. Mutat Res. 2018;832-833:52-60. https://doi.org/10.1016/j.mrgentox. 2018.06.018.
- Almeida LL, Teixeira ÁA, Soares AF, et al. Effects of melatonin in rats in the initial third stage of pregnancy exposed to sub-lethal doses of herbicides. Acta Histochem. 2017;119(3):220-227. https://doi.org/10.1016/j.acthis.2017. 01.003.
- Kennaway DJ, Stamp GE, Goble FC. Development of melatonin production in infants and the impact of prematurity. J Clin Endocrinol Metab. 1992;75(2):367-369. https://doi.org/10.1210/jcem.75.2.1639937.
- Fernando S, Wallace EM, Vollenhoven B, et al. Melatonin in assisted reproductive technology: a pilot double-blind randomized placebo-controlled clinical trial. Front Endocrinol (Lausanne). 2018;9:545. https://doi.org/10.3389/fendo.2018.00545.
- Wurtman RJ, Axelrod J, Potter LT. The uptake of H3-melatonin in endocrine and nervous tissues and the effects of constant light exposure. J Pharmacol Exp Ther. 1964;143(3):314-318.
- Brzezinski A, Seibel MM, Lynch HJ, et al. Melatonin in human preovulatory follicular fluid. J Clin Endocrinol Metab. 1987;64(4):865-867. https://doi.org/10.1210/jcem-64-4-865.
- Okatani Y, Okamoto K, Hayashi K, et al. Maternal-fetal transfer of melatonin in pregnant women near term. J Pineal Res. 1998;25:129-134. https://doi.org/10.1111/j.1600-079x.1998.tb00550.x.
- Tamura H, Takasaki A, Taketani T, et al. Melatonin as a free radical scavenger in the ovarian follicle. Endocr J. 2013;60(1):1-13. https://doi.org/10.1507/endocrj.ej12-0263.
- Silman RE. Melatonin: a contraceptive for the nineties. Eur J Obstet Gynecol Reprod Biol. 1993;49(1-2):3-9. https://doi.org/10.1016/0028-2243(93)90099-x.
- Закурина А.Н., Коржевский Д.Э., Павлова Н.Г. Плацентарная недостаточность – морфофункциональные параллели // Журнал акушерства и женских болезней. – 2010. – Т. 59. – № 5. – С. 51−55. [Zakurina AN, Korzhevskiy DE, Pavlova NG. Platsentarnaya nedostatochnost’ − morfofunktsional’nyye paralleli. Journal of obstetrics and women’s diseases. 2010;59(5):51-55. (In Russ.)]
- Spencr RN, Car DJ, David AL. Treatment of poor placentation and the prevention of associated adverse outcomes – what does the future hold? Prenatal Diagnosis. 2014;34(7):677-684. https://doi.org/10.1002/pd.4401.
- Deter RL, Lee W, Sangi-Haghpeykar H. Fetal growth cessation in late pregnancy: its impact on predicted size parameters used to classify small for gestational age neonates. J Matern Fetal Neonatal Med. 2015;28(7):755-765. https://doi.org/10.3109/14767058.2014.934219.
- Kanwal G, Sakshi N. Current trends in management of fetal growth restriction. J Fetal Med. 2014;1(3):125-129. https://doi.org/10.1007/s40556-015-0027-1.
- Шайманов А.К., Кайралнева Г.Д., Есенгулова Ж.Ш. Гестоз – одна из причин материнской cмертности // Актуальные проблемы акушерства, гинекологии и перинатологии: материалы конференции. – Алматы, 2003. – С. 169−170. [Shaimanov AK, Kairalneva GD, Esengulova ZhSh. Gestoz – odna iz prichin materinskoi cmertnosti. (Conference proceedings) Aktual’nyye problemy akusherstva, ginekologii i perinatologii Almaty; 2003. Р. 169-170. (In Russ.)]
- Reiter RJ, Tan DX, Galano A. Melatonin: exceeding expectations. Physiology (Bethesda). 2014;29(5):325-333. https://doi.org/10.1152/physiol.00011.2014.
- Rizzo P, Raffone E, Benedetto V. Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial. Eur Rev Med Pharmacol Sci. 2010;14(6):555-561.
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