Email this article Respiratory viral infections including caused by coronaviruses in oncological and oncohematological patients
- Authors: Kuleshova A.V.1, Iskova I.P.2, Kiseleva E.E.1, Chebotkevich V.N.1
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Affiliations:
- Russian Research Institute of Hematology and Transfusiology of the Federal Medical-Biological Agency
- Kirov Clinical Interdistrict Hospital
- Issue: Vol 21, No 3 (2021)
- Pages: 119-122
- Section: Conference proceedings
- URL: https://ogarev-online.ru/MAJ/article/view/78565
- DOI: https://doi.org/10.17816/MAJ78565
- ID: 78565
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Abstract
BACKGROUND: Patients with cancer are prone to developing infectious complications. They significantly aggravate the course of the underlying disease and worsen the quality of life of patients. The emergence of infections is largely promoted by immunosuppression associated with the use of cytostatic drugs, high-dose chemotherapy and hematopoietic stem cell transplantation in hematological cancer patients. Among infectious agents, respiratory viruses, especially influenza viruses, play an important role. The urgency of this problem has increased many times in connection with the development of the COVID-19 pandemic.
AIM: To study the features of the course of respiratory infections, including coronavirus (seasonal and COVID-19), infections in cancer and oncohematological patients during hospitalization and in outpatient settings.
MATERIALS AND METHODS: The study of the frequency and course of infectious complications in cohorts of patients with oncological diseases, who were under dispensary supervision in the polyclinic in Kirovsk, Leningrad region. Retrospective analysis of the frequency and characteristics of the course of coronavirus infection caused by HCoVs (OC43, 229E, NL63, HKU1) in patients treated at the clinics of the Russian research institute of Hematology and Transfusionology. Prospective study of the coronavirus COVID-19 of patients hospitalized at the Russian research institute of Hematology and Transfusionology and at the Kirov interdistrict hospital in Leningrad Region during the period of its conversion to specialized infection diseases hospital.
RESULTS: Coronavirus infection caused by HCoVs (OC43, 229E, NL63, HKU1), occurs in hematological cancer patients more often in association with other respiratory viruses. In the cases of detection of the SARS-CoV-2 in hospitalized patients, they need to be transferred to specialized infectious hospitals.
CONCLUSIONS: Respiratory viral infections are risk factors in cancer and oncohematological patients. Outpatient oncological and oncohematological patients require constant dispensary observation and special attention during the COVID-19 pandemic, outbreaks of influenza and other viral infections.
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##article.viewOnOriginalSite##About the authors
Alena V. Kuleshova
Russian Research Institute of Hematology and Transfusiology of the Federal Medical-Biological Agency
Author for correspondence.
Email: alenabs@yandex.ru
Head of the Bacteriological Laboratory, doctor-bacteriologist
Russian Federation, Saint PetersburgInna P. Iskova
Kirov Clinical Interdistrict Hospital
Email: alenabs@yandex.ru
oncologist
Russian Federation, Leningrad Region, KirovskEkaterina E. Kiseleva
Russian Research Institute of Hematology and Transfusiology of the Federal Medical-Biological Agency
Email: alenabs@yandex.ru
PhD (Biol.), Senior Researcher the Bacteriological Laboratory
Russian Federation, Saint PetersburgVitaliy N. Chebotkevich
Russian Research Institute of Hematology and Transfusiology of the Federal Medical-Biological Agency
Email: alenabs@yandex.ru
Dr. Sci. (Med.), Professor, Head of the Department of the Bacteriology
Russian Federation, Saint PetersburgReferences
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