Application of radiomics in osteoporosis detection — current capabilities and future prospects (a review)

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Abstract

The prevalence of osteoporotic fractures continues to increase as the population ages due to demographic transition. This is particularly relevant for developed countries, including Russia. Radiomics may emerge as a valuable tool for osteoporosis detection.

This review demonstrates the development and application of radiomics in diagnosing oncological and non-oncological diseases including osteoporosis.

A literature search was conducted using the databases PubMed, Google Scholar, and eLibrary over the past 5 years. Data on the prevalence and epidemiology of osteoporosis were obtained from publications in the last 15 years. The search was performed using the following keywords: "radiomic", "osteoporosis", "texture", "magnetic resonance imaging", "computed tomography", "non-oncological radiomics", «магнитно-резонансная томография» ("magnetic resonance imaging"), «компьютерная томография» ("computed tomography"), «радиомика» ("radiomics"), «остеопороз» ("osteoporosis"), «текстурный анализ» ("texture analysis"), «радиомический анализ» ("radiomic analysis"). Data from original clinical studies were included. In total, 247 articles were found and analyzed. Finally, 59 studies were selected for the review.

The number of studies examining the potential of radiomics in detecting osteoporosis was limited. Further research is required to explore the potential of radiomic analysis using computed tomography and magnetic resonance imaging for detecting osteoporosis compared to established methods such as dual-energy X-ray absorptiometry and the FRAX (Fracture Risk Assessment Tool) algorithm.

About the authors

Anton I. Chugaev

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies; MRI24

Author for correspondence.
Email: chugaev020379@yandex.ru
ORCID iD: 0009-0006-8930-9320
Russian Federation, Moscow; Moscow

Yuriy A. Vasilev

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies

Email: VasilevYA1@zdrav.mos.ru
ORCID iD: 0000-0002-5283-5961
SPIN-code: 4458-5608

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Alexey V. Petraikin

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies

Email: alexeypetraikin@gmail.com
ORCID iD: 0000-0003-1694-4682
SPIN-code: 6193-1656

MD, Dr. Sci. (Medicine)

Russian Federation, Moscow

Ivan A. Blokhin

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies

Email: i.blokhin@npcmr.ru
ORCID iD: 0000-0002-2681-9378
SPIN-code: 3306-1387

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Anton V. Vladzymyrskyy

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies

Email: VladzimirskijAV@zdrav.mos.ru
ORCID iD: 0000-0002-2990-7736
SPIN-code: 3602-7120

MD, Dr. Sci. (Medicine)

Russian Federation, Moscow

Olga V. Omelyanskaya

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies

Email: OmelyanskayaOV@zdrav.mos.ru
ORCID iD: 0000-0002-0245-4431
SPIN-code: 8948-6152
Russian Federation, Moscow

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