The Effect of Selective Hypothermia of the Cerebral Cortex on Metabolism in Patients with Prolonged Impairment of Consciousness
- Authors: Mengistu E.M.1,2, Petrova M.V.1,2, Shevelev O.A.1,2
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Affiliations:
- Federal Scientific and Clinical Center of Intensive Care Medicine and Rehabilitology
- Peoples Friendship University of Russia
- Issue: Vol 4, No 2 (2022)
- Pages: 122-124
- Section: SHORT COMMUNICATION
- URL: https://ogarev-online.ru/2658-6843/article/view/108417
- DOI: https://doi.org/10.36425/rehab108417
- ID: 108417
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Abstract
A pilot study was conducted among patients with chronic impaired consciousness in order to assess the response of energy expenditure at rest (REE) during craniocerebral hypothermia. It was found that REE increased in 70.59% of patients, and decreased in 29.41%. It is assumed that the decrease in REE is associated with preserved metabolic activity in the intact parts of the cerebral cortex and may indicate the presence of rehabilitation potential, and the decrease indicates the presence of gross damage that excluded the selectivity of hypothermic exposure.
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##article.viewOnOriginalSite##About the authors
Elias M. Mengistu
Federal Scientific and Clinical Center of Intensive Care Medicine and Rehabilitology; Peoples Friendship University of Russia
Email: drmengistu@mail.ru
ORCID iD: 0000-0002-6928-2320
SPIN-code: 1387-7508
Russian Federation, 25-2 Petrovka street, Moscow, 107031; Moscow
Marina V. Petrova
Federal Scientific and Clinical Center of Intensive Care Medicine and Rehabilitology; Peoples Friendship University of Russia
Email: mpetrova@fnkcrr.ru
ORCID iD: 0000-0003-4272-0957
SPIN-code: 9132-4190
MD, Dr. Sci. (Med.)
Russian Federation, 25-2 Petrovka street, Moscow, 107031; MoscowOleg A. Shevelev
Federal Scientific and Clinical Center of Intensive Care Medicine and Rehabilitology; Peoples Friendship University of Russia
Author for correspondence.
Email: shevelev_o@mail.ru
ORCID iD: 0000-0002-6204-1110
SPIN-code: 9845-2960
MD, Dr. Sci. (Med.), Professor
Russian Federation, 25-2 Petrovka street, Moscow, 107031; MoscowReferences
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