Email this article Macroscopic anatomy of the fetal nasal cavity
- Authors: Lutsai E.D.1, Anikin M.I.1, Murtazina N.I.1, Naidenova S.I.1, Anisimov A.V.1, Kirksova L.S.2, Neprokina A.V.3
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Affiliations:
- Orenburg State Medical University
- Orenburg Regional Hospital
- State Medical University
- Issue: Vol 6, No 1 (2021)
- Pages: 9-13
- Section: ENT Disorders
- URL: https://ogarev-online.ru/2500-1388/article/view/59582
- DOI: https://doi.org/10.35693/2500-1388-2021-6-1-9-13
- ID: 59582
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Abstract
Objectives – to describe the macromicroscopic anatomy of the nasal cavity in the intermediate fetal period of human ontogenesis.
Material and methods. The object of the study was horizontal histotopograms of the nose of 15 fetuses of both genders at the age of 19–22 weeks of the intermediate fetal period of ontogenesis. The study used the method of macromicroscopic preparation, the modified method of saw cuts according to N.I. Pirogov, and the histotopographic method.
Results. On the horizontal histotopographic sections the external nose was shaped like a triangle. The structures of the external nose were covered with skin soldered to the underlying tissues. In soft tissues, there was a large accumulation of arterial and venous vessels, nerves, and glands. In the intermediate fetal period, the nasal passages had the shape of a triangle, with the base turned to the nasal part of the pharynx.
It was found that the anterior-posterior size of the nasal septum in fetuses of the intermediate fetal period was 14.05±4.34 mm, with a range of fluctuations from 5.75 to 19.85 mm. The anterior-posterior size of the nasal septum in female fetuses was greater than the anterior-posterior size of the septum of male fetuses. The value of the width of the nasal septum was the maximum in the lower third, and reached up to 2.54±0.67 mm. The narrowest part of the nasal septum was its middle third, the value was 1.63±0.47 mm. The areas of the nasal passages had no bilateral differences.
Conclusion. In the intermediate fetal period there is the establishment of qualitative and quantitative macromicroscopic anatomy of the nasal cavity. All the main structures are determined: the nasal septum, nasal conchs, mucosa, and blood vessels. Sexual differences begin to form, and there are no bilateral differences. Quantitative characteristics of the structures of the nasal cavity in fetuses can serve as a justification for early surgical intervention in choanal atresia.
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##article.viewOnOriginalSite##About the authors
Elena D. Lutsai
Orenburg State Medical University
Email: elut@list.ru
ORCID iD: 0000-0002-7401-6502
PhD, Professor, Department of Human anatomy, Director of the Institute of professional education
Russian Federation, OrenburgMaksim I. Anikin
Orenburg State Medical University
Email: m.anikin@mail.ru
ORCID iD: 0000-0002-1900-3039
PhD, Associate professor, the Head of the Department of Otorhinolaryngology
Russian Federation, OrenburgNuriya I. Murtazina
Orenburg State Medical University
Author for correspondence.
Email: N.I.Murtazina@mail.ru
ORCID iD: 0000-0002-7898-5511
assistant of the Department of Otorhinolaryngology
Russian Federation, OrenburgSvetlana I. Naidenova
Orenburg State Medical University
Email: N.I.Murtazina@mail.ru
ORCID iD: 0000-0003-0309-7541
assistant of the Department of Human anatomy
Russian Federation, OrenburgAnton V. Anisimov
Orenburg State Medical University
Email: anton-979@mail.ru
ORCID iD: 0000-0003-1439-754X
4th year student
Russian Federation, OrenburgLidiya S. Kirksova
Orenburg Regional Hospital
Email: lkirksova@bk.ru
ORCID iD: 0000-0001-5313-6719
otorhinolaryngologist
Russian Federation, OrenburgAnastasiya V. Neprokina
State Medical University
Email: neprokina@mail.ru
ORCID iD: 0000-0003-1117-0163
assistant of the Department of Human anatomy
Russian Federation, OrenburgReferences
- Marchenko NP, Shevchenko EA. Cat scream syndrome: prenatal ultrasound findings. Prenatal diagnosis. 2017;16(3):265-270. (In Russ.). [Марченко Н.П., Шевченко Е.А. Синдром Лежена («кошачьего крика»): пренатальные ультразвуковые находки. Пренатальная диагностика. 2017;16(3):265-270]. doi: 10.21516/2413-1458-2017-16-3-265-270
- Medvedev MV, Sosynyuk VA. Prenatal diagnosis of rare congenital malformations and syndromes. XXXV. Cornelia de Lange syndrome. Prenatal diagnosis. 2009;8(3):203-207. (In Russ.). [Медведев М.В., Сосынюк В.А. Пренатальная диагностика редких врожденных пороков и синдромов. ХХХV. Синдром Корнелии де Ланге. Пренатальная диагностика. 2009;8(3):203-207].
- Marchenko NP, Shevchenko EA, Rozhkova TV, Boldyreva OV. Prenatal diagnosis of Treacher Collins syndrome (maxillofacial dysostosis). Prenatal diagnosis. 2017;16(1):75-78. (In Russ.). [Марченко Н.П., Шевченко Е.А., Рожкова Т.В., Болдырева О.В. Пренатальная диагностика синдрома Тричера Коллинза (челюстно-лицевой дизостоз). Пренатальная диагностика. 2017;16(1):75-78]. doi: 10.21516/2413-1458-2017-16-1-75-78
- Neskey D, Eloy JA, Casiano RR. Nasal, septal, and turbinate anatomy and embryology. Otolaryngol Clin North Am. 2009;42:193-205.
- Kotova EN, Bogomil'skiy MR. Transnasal endoscopic surgery of congenital choanal atresia in children. Bulletin of RSMU. 2015;3:41-43. (In Russ.). [Котова Е.Н., Богомильский М.Р. Трансназальная эндоскопическая хирургия врожденной атрезии хоан у детей. Вестник РГМУ. 2015;3:41-43].
- Tikhomirova IA. Syndrome of violation of nasal breathing in children: diagnosis and choice of treatment tactics. The Doctor. 2012;4:26-31. (In Russ.). [Тихомирова И.А. Синдром нарушения носового дыхания у детей: диагностика и выбор лечебной тактики. Врач. 2012;4:26-31].
- Piskunov VS. Anatomical features of the structure and shape of the choanas. Russian Rhinology. 2006;1:33-34. (In Russ.). [Пискунов В.С. Анатомические особенности строения и формы хоан. Российская ринология. 2006;1:33-34].
- Piskunov GZ. Anatomy of the nose and paranasal sinuses. Klin. rinologiya. M.: MIA, 2017:49-103. (In Russ.). [Пискунов Г.З. Анатомия носа и околоносовых пазух. Клиническая. ринология. М.: МИА, 2017: 49-103].
- Khrappo NS. The nose in the whole skull system. Samara: SamGMU, 1999. (In Russ.). [Храппо Н.С. Нос в системе целого черепа. Самара: СамГМУ, 1999].
- Holt GR. Nasal region. Otolaryngologic Clinics of North America. 2009, Aug:615-619.
- Chkadua TZ, Ivanova MD, Daminov RO, et al. Restoration of nasal breathing and elimination of deformity of the osteochondral part of the nose in a patient with right-sided choanal atresia and congenital left-sided cleft lip and palate. Stomatology. 2016;95(1):35-39. (In Russ.). [Чкадуа Т.З., Иванова М.Д., Даминов Р.О. и др. Восстановление носового дыхания и устранение деформации костно-хрящевого отдела носа у пациента с правосторонней атрезией хоан и врожденной левосторонней расщелиной губы и неба. Стоматология. 2016;95(1):35-39]. doi: 10.17116/stomat201695135-39
- Gayvoronskiy IV, Markeyeva MV, Aleshkina YuA, Tarasova NV. Characteristics of the structures of the posterior parts of the nasal cavity in the age aspect in children. Journal of Anatomy and Histopathology. 2020;9(3):9-15. (In Russ.). [Гайворонский И.В., Маркеева М.В., Алешкина Ю.А., Тарасова Н.В. Характеристика структур задних отделов полости носа в возрастном аспекте у детей. Журнал анатомии и гистопатологии. 2020;9(3):9-15]. doi: 10.18499/2225-7357-2020-9-3-9-15
- Gayvoronskiy IV. Features of the structure of intranasal structures in lepto-, meso- and platyrins. Morphology. 2010;137(4):51-52. (In Russ.). [Гайворонский И.В. Особенности строения внутриносовых структур у лепто-, мезо- и платиринов. Морфология. 2010;137(4):51-52].
- Bruyaka RA. Endonasal endoscopic surgery for some diseases of the paranasal sinuses in children. Russian Otorhinolaryngology. 2012;4(59):26-29. (In Russ.). [Бруяка Р.А. Эндоназальная эндоскопическая хирургия при некоторых заболеваниях околоносовых пазух у детей. Российская оториноларингология. 2012;4(59):26-29].
- Markeyeva MV, Aleshkina OYu, Tarasova NV, Gayvoronskiy IV. Anatomical features of the structure of the ethmoid labyrinth and the structure of the nasal cavity in childhood. Vestnik Rossiyskoy voyenno-meditsinskoy akademii. 2020;4(72):95-99. (In Russ.). [Маркеева М.В., Алешкина О.Ю., Тарасова Н.В., Гайворонский И.В. Анатомические особенности строения решетчатого лабиринта и структур полости носа в детском возрасте. Вестник Российской военно-медицинской академии. 2020;4(72):95-99].
- Minova EN, Khmeleva AV, Volodeyev AV, et al. Embryogenesis of the lateral wall of the nose and lacrimal ducts from 4 to 20 weeks. Universitetskaya meditsina Urala. 2016;4:15-18. (In Russ.). [Минова Е.Н., Хмелева А.В., Володеев А.В. и др. Эмбриогенез латеральной стенки носа и слезоотводящих путей с 4 по 20 неделю. Университетская медицина Урала. 2016;4:15-18].
- Baranov KK, Zyabkin IV, Pikhurovskaya AA, Bogomil'skiy MR. Anatomical features of inferior turbinate hypertrophy in children. Head and Neck Journal. 2019;7(3):23-27. (In Russ.). [Баранов К.К., Зябкин И.В., Пихуровская А.А., Богомильский М.Р. Анатомические особенности гипертрофии нижних носовых раковин у детей. Голова и шея. 2019;7(3):23-27].
- Kuznyak NB, Boychuk OM, Protsak TV, Bambulyak AV. The development of nasal conchas in the prefetal period of human ontogenesis. Ukrayinsʹkyy morfolohichnyy alʹmanakh. 2012;10(4):56-58. [Кузняк Н.Б., Бойчук О.М., Процак Т.В., Бамбуляк А.В. Розвиток носових раковин в передплодовому періоді онтогенезу людини. Український морфологічний альманах. 2012;10(4):56-58].
- Mikhaylov YuKh. Some theoretical and methodological problems modern rhinology. Voyenno-meditsinskiy zhurnal. 2013;27(6):52-56. (In Russ.). [Михайлов Ю.Х. Некоторые теоретические и методологические проблемы современной ринологии. Военно-медицинский журнал. 2013;27(6):52-56].
- Bicsak A, Vasvari G, Patonay L. The relations of the development of the nasomaxillary complex and nasal septal deviation. 1-st Jeint Muting of EACA and AACA. 2003;July 7-11:139-140.
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