A developed treatment method for superficial and partial thickness localized burns: Clinical and morphological assessment

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Abstract

Objectives – to prove the effectiveness of the new developed method of treatment of patients with localized superficial and partial thickness burns (gel and silver coating plus ultraviolet radiation of the wound and magnetic therapy).

Material and methods. The treatment of local burn wound infection was analyzed in 29 patients with I-II degree localized burns during the all phases of the wound healing process. The wound material was obtained in accordance with the requirements of the Guidelines МУ 4.2.2039-05 "The technique of collection and transportation of biomaterials in microbiological laboratories". The material was delivered to the laboratory in test tubes with a transport medium under isothermal conditions at a temperature of 20–22°C within a day after collection.

Results. The tests revealed no significant differences in the studied characteristics between the compared groups (р>0.05, р=0.55, ÷2=3.841).

Conclusion. We consider the developed method of local treatment of superficial and partial thickness localized burns as a rather promising, feasible method having its own significance and intended for the prevention and treatment of local wound infection in all phases of the wound healing process.

About the authors

A. V. Tolstov

Samara State Medical University

Author for correspondence.
Email: tolstovanatoly@mail.ru
ORCID iD: 0000-0002-7433-8982

PhD, Professor, Department of Operative surgery and clinical anatomy with a course of innovative technologies

Russian Federation, Samara

I. V. Novikov

Samara State Medical University

Email: tolstovanatoly@mail.ru
ORCID iD: 0000-0002-6855-6828

postgraduate student of the Department of Operative surgery and clinical anatomy with a course of innovative technologies

Russian Federation, Samara

I. V. Podsevalova

Samara State Medical University

Email: tolstovanatoly@mail.ru
ORCID iD: 0000-0001-6350-2591

PhD, Associate Professor of the Department of Human anatomy

Russian Federation, Samara

A. S. Voronin

Samara State Medical University

Email: tolstovanatoly@mail.ru
ORCID iD: 0000-0002-8472-3796

PhD, Associate Professor of the Department of Operative surgery and clinical anatomy with a course of innovative technologies

Russian Federation, Samara

S. S. Dydykin

Sechenov First Moscow State Medical University

Email: tolstovanatoly@mail.ru
ORCID iD: 0000-0002-1273-0356

PhD, Professor, Head of the Department of Operative surgery and topographic anatomy

Russian Federation, Moscow

V. V. Alipov

Saratov State Medical University named after V.I. Razumovsky

Email: tolstovanatoly@mail.ru
ORCID iD: 0000-0002-1859-0825

PhD, Professor, Head of the Department of Operative surgery and topographic anatomy

Russian Federation, Saratov

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2. Figure 1. Touch smears of the burn wound of the patient of the main group, day 4. A. Neutrophilic white blood cells with signs of degeneration, vacuoles in the structure of the macrophages. Azur-eosin staining according to Romanovsky (x100). B. Esterase granules in macrophages. ICC. Reaction with а-naphthyl acetate (x100).

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3. Figure 2. Touch smears of the burn wound of the patient of the control group, day 4. Signs of microbial contamination of the wound. Degenerative changes and cytolysis of neutrophilic leukocytes, single macrophages. Azur-eosin staining according to Romanovsky (x100).

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4. Figure 3. Touch smears of the burn wound of the patient of the main group, day 12. Accumulation of collagen fibers infiltrated by neutrophilic leukocytes. Azur-eosin staining according to Romanovsky (x40).

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5. Figure 4. Touch smears of the burn wound of the patient of the control group, day 12. Isolated macrophages with granules with esterase. ICC. Reaction with a-naphthyl acetate (x40).

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Copyright (c) 2020 Tolstov A.V., Novikov I.V., Podsevalova I.V., Voronin A.S., Dydykin S.S., Alipov V.V.

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