Coagulation profile depending on ABО blood group system
- Authors: Gusyakova O.A.1, Gilmiyarova F.N.1, Ereshchenko A.A.1, Kuzmicheva V.I.1, Borodina I.A.1, Potyakina E.E.1
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Affiliations:
- Samara State Medical University
- Issue: Vol 4, No 2 (2019)
- Pages: 4-8
- Section: Internal medicine
- URL: https://ogarev-online.ru/2500-1388/article/view/43727
- DOI: https://doi.org/10.35693/2500-1388-2019-4-2-4-8
- ID: 43727
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Abstract
Objectives – to compare the parameters of hemostasis in representatives of various blood groups using the ABО system.
Material and methods. The study involved 51 people (mean age 19.8±0.5 year). The parameters of the coagulation, anticoagulation and fibrinolytic systems were determined for all the examined persons. The following hemostasis parameters were investigated: coagulation factors (II, VII, VIII, IX, X, XI, XII), APTT, prothrombin time, plasminogen, antiplasmin, antithrombin III, protein C.
Results. The obtained results indicate the presence of biological variation of blood coagulation parameters depending on the antigenic affiliation of the blood group according to the ABО system, which is manifested in a change in the concentration and activity of a number of coagulation factors. The revealed tendencies made it possible to form a coagulation profile depending on the group of blood in the ABО system.
Conclusion. The study of variability of coagulation parameters, depending on the group of blood in the ABО system, is an important step towards the formation of personalized approach in laboratory research.
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##article.viewOnOriginalSite##About the authors
Oksana A. Gusyakova
Samara State Medical University
Email: bio-sam@yandex.ru
ORCID iD: 0000-0002-5619-4583
PhD, Associate Professor, Head of the Chair of fundamental and clinical biochemistry with laboratory diagnostics, Head of the Clinical and Diagnostic Laboratory
Russian Federation, SamaraFrida N. Gilmiyarova
Samara State Medical University
Email: bio-sam@yandex.ru
ORCID iD: 0000-0001-5992-3609
Honored PhD, Professor, Chair of fundamental and clinical biochemistry with laboratory diagnostics
Russian Federation, SamaraAlyona A. Ereshchenko
Samara State Medical University
Author for correspondence.
Email: bio-sam@yandex.ru
ORCID iD: 0000-0002-4221-4440
assistant of the Chair of fundamental and clinical biochemistry with laboratory diagnostics
Russian Federation, SamaraValeriya I. Kuzmicheva
Samara State Medical University
Email: bio-sam@yandex.ru
ORCID iD: 0000-0002-5232-1549
resident of the Chair of fundamental and clinical biochemistry with laboratory diagnostics
Russian Federation, SamaraInessa A. Borodina
Samara State Medical University
Email: bio-sam@yandex.ru
ORCID iD: 0000-0001-7115-6430
resident of the Chair of fundamental and clinical biochemistry with laboratory diagnostics
Russian Federation, SamaraElena E. Potyakina
Samara State Medical University
Email: bio-sam@yandex.ru
ORCID iD: 0000-0002-1382-1831
assistant of the Chair of fundamental and clinical biochemistry with laboratory diagnostics
Russian Federation, Samara, RussiaReferences
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