METHOD OF DIAGNOSIS OF ORAL MANIFESTATIONS OF HEMATOLOGIC MALIGNANCIES BY USING CONCENTRATIONS OF IMMUNOGLOBULIN A AND G ANTIBODIES TO GLIADINE AND TRANSGLUTAMINASE


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Abstract

Aim - developing of the new method of diagnosis of oral manifestations of hematologic malignancies by using concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase in saliva. Materials and methods. The condition of oral mucosa and concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase were assessed in 90 patients with acute and chronic leukemia. Results. After polychemiotherapy their oral status and concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase changed significantly. Conclusion. The study will help develop effective method of diagnosis of oral manifestations of hematologic malignancies.

About the authors

MV V Svechnikova

Samara State Medical University

Email: umka86@list.ru
assistant of the Department of Therapeutic Dentistry, Samara State Medical University.

EM M Gilmiyarov

Samara State Medical University

Email: terstom-samara@yandex.ru
PhD, professor head of the Department of Therapeutic Dentistry, Samara State Medical University.

IA A Selezneva

Samara State Medical University

Email: innola@mail.ru
PhD, associate professor of the Department of Fundamental and Clinical Biochemistry with Laboratory Diagnosis.

IM M Fedyaev

Samara State Medical University

Email: terstom-samara@yandex.ru
PhD, professor of the Department of the Oral and Maxillofacial Surgery.

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Copyright (c) 2016 Svechnikova M.V., Gilmiyarov E.M., Selezneva I.A., Fedyaev I.M.

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