Email this article The effect of sublingual immunotherapy on the control level of bronchial asthma
- Authors: Nagatkin DA1
-
Affiliations:
- Самарский государственный медицинский университет
- Issue: Vol 13, No 5-6 (2013)
- Pages: 53-56
- Section: Articles
- URL: https://ogarev-online.ru/2410-3764/article/view/24788
- DOI: https://doi.org/10.17816/2072-2354.2013.0.5-6.53-56
- ID: 24788
Cite item
Full Text
Abstract
Allergic asthma and allergic rhinitis some of the most common forms of atopic diseases. Despite the wide range of pharmaceutical products for the treatment of allergic diseases, the main point of their application remains symptomatic treatment. Allergen-specific immunotherapy to date remains the only method of pathogenic effects on the course of allergic diseases. The aim of our work was to evaluate the effects of sublingual formulations for allergen-specific therapy on the level of control and quality of life of patients suffering from allergic form of bronchial asthma and proven sensitization to pollens of trees. The study involved 37 patients who had been previously examined by carrying out skin prick tests with allergens to detect sensitization to pollen of birch, alder and hazel. Evaluated the following parameters: the results of ACT (Asthma Control Test) test, ACQ-5 (Asthma Control Questionary) test parameters were evaluated quality of life using the SF-36 questionnaire (The Short Form 36), and spirometry. Carrying sublingual immunotherapy significantly improved the quality of life of patients and increase the performance of control of their disease.
References
- Masoli M. et al. The global burden of asthma: executive summary of the GINA Dissemination Committee report / M. Masoli [et al].//Allergy. - 2004 May - V.59(5).- P:469-478
- Beasley R. The Global Burden of Asthma Report, Global Initiative for Asthma (GINA)/ R. Beasley// Available from http://www.ginasthma.org.- 2012
- Глобальная стратегия лечения и профилактики бронхиальной астмы. Пересмотр 2006/ Под ред. Чучалина А.Г. - М.: Изд. Дом «Атмосфера». - 2007. - 22с
- Pawankar R. et al. WAO White book of allergy./ R. Pawankar [et al.].// Available from http://www.worldallergy.org/UserFiles/file/WAO-White-Book-on-Allergy_web.pdf - 2011.
- Greisner W.A. 3rd, Settipane R.J., Settipane G.A. Co-existence of asthma and allergic rhinitis: a 23-year follow-up study of college students./ W.A. Greisner 3rd, R.J. Settipane, G.A. Settipane // Allergy Asthma Proc. - 1998 Jul-Aug. -V.19(4) - P.185-188
- Corren J. Allergic rhinitis and asthma: how important is the link?/ J. Corren // J. Allergy Clin. Immunol. - 1997 Feb. - V.99(2).- P.781-786
- Leynaert B. et al. Perennial rhinitis: An independent risk factor for asthma in nonatopic subjects: results from the European Community Respiratory Health Survey/ B. Leynaert [et al.].//J Allergy Clin. Immunol.-1999 Aug. - V.104(2 Pt 1). P.301-304
- Gergen P.J., Turkeltaub P.C. The association of individual allergen reactivity with respiratory disease in a national sample: data from the second National Health and Nutrition Examination Survey, 1976-80 (NHANES II)./ P.J.Gergen, P.C. Turkeltaub //J. Allergy Clin. Immunol. - 1992 Oct. - V.90(4 Pt 1). - P.579-588
- Bufe A. et al. Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy./ A. Bufe [et al.] .// J. Allergy Clin Immunol - 2009 Jan. - V.123(1). - P.167-173
- Ott H. et al. Efficacy of grass pollen sublingual immunotherapy for three consecutive seasons and after cessation of treatment: the ECRIT study. / H. Ott [et al.]. //Allergy - 2009 Sep. - V.64(9). - P.1394-1401
- Calderon M.A. et al. An evidence-based analysis of house dust mite allergen immunotherapy: A call for more rigorous clinical studies./ M.A. Calderon [et al.] .//J. Allergy Clin Immunol - 2013 Dec. - V.132(6). - P.1322-1326
Supplementary files
