COMPARISON OF PREDICTIVE CAPABILITYOF CYTOMORPHOLOGICAL AND CRYSTALLOGRAPHIC METHODSOF BREAST SECRET ASSESSMENT IN WOMEN OF HIGH RISK FOR EARLY HYPOGALACTIA

The article is devoted to the assessment of the prognostic significance of the morphological and crystallographic methods for studying mammary glands secretion in postpartum women with a history of placental insufficiency pregnancy to select the most informative and timely improvement of this pathology. The early detection of hypogalactia in 210 postpartum women with placental insufficiency of varying severity during gestation was performed by determining morphological type of mammary glands secretion smear and crystallographic method. To calculate the sensitivity, specificity, positive and negative predictive value, the diagnostic accuracy of methods of early lactational disorders within the first 7 days of postpartum period we investigated subjective and objective clinical hypogalactia signs in the mother and the child, determined the amount of milk by gravimetric method, additionally measured the temperature in the armpit and lower quadrant of the left breast. Results of the study showed cytomorphological and crystallographic techniques to be comparable, but crystallography has the advantage and the detection rate of early hypogalactia and ease of use. This method has the highest predictive value (Se 99,3%, Sp 97,2%, P 98,4%) for the early hypogalactia compared with another studied method.

early hypogalactia, placental insufficiency, crystallography, smear morphotypes of the mammary glands secretion, evidence-based medicine