Aortic coarctation in pregnant women

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Abstract

This article presents a review of the etiology, pathogenesis, clinical manifestations, and diagnostic approaches to aortic coarctation, which accounts for approximately 6%–7% of all congenital heart defects and occurs in pregnancy with a frequency of about 1 case per 4500 deliveries. For a long time, pregnancy in women with aortic coarctation was considered extremely high risk, and pregnancy termination was often recommended. Pregnancy in women with unrepaired aortic coarctation is frequently associated with various complications, including uncontrolled hypertension, preeclampsia, hypertensive crisis, congestive heart failure, stroke, and aortic rupture or dissection.

At present, there are no clear guidelines or a unified approach to the management of pregnancy in women with aortic coarctation. Recent studies indicate that, with appropriate management, pregnancy may proceed without serious complications. The main reasons for hospitalization during pregnancy in these patients include heart failure, uncontrolled hypertension, and supraventricular arrhythmias. Therefore, strict blood pressure control appears to be a key component in the management of pregnant women with this condition. A clinical case describing pregnancy management and delivery in a patient with newly diagnosed aortic coarctation is also presented.

About the authors

Vera S. Belousova

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: belousova_v_s@staff.sechenov.ru
ORCID iD: 0000-0001-8332-7073
SPIN-code: 6026-9008

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Moscow

Amalia A. Arakelyants

Sechenov First Moscow State Medical University (Sechenov University)

Email: nxrrimma@mail.ru
ORCID iD: 0000-0002-1243-2471
SPIN-code: 4990-6008

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, Moscow

Yulia E. Mokrova

Sechenov First Moscow State Medical University (Sechenov University)

Email: mokrova_yulya_03@mail.ru
ORCID iD: 0009-0002-2500-5062
Russian Federation, Moscow

Yulia A. Sergienko

Sechenov First Moscow State Medical University (Sechenov University)

Email: mokrova_yulya_03@mail.ru
ORCID iD: 0009-0003-6020-1330
Russian Federation, Moscow

Irina M. Bogomazova

Sechenov First Moscow State Medical University (Sechenov University)

Email: bogomazova_i_m@staff.sechenov.ru
ORCID iD: 0000-0003-1156-7726
SPIN-code: 9414-1218

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, Moscow

Madina A. Kardanova

Sechenov First Moscow State Medical University (Sechenov University)

Email: kardanova_m_a@staff.sechenov.ru
ORCID iD: 0000-0002-4315-0717
SPIN-code: 3895-9666

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, Moscow

Svetlana V. Pesegova

Sechenov First Moscow State Medical University (Sechenov University)

Email: pesegova_s_v@staff.sechenov.ru
ORCID iD: 0000-0002-1339-5422
SPIN-code: 8891-9490

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Oksana V. Skorobogatova

Sechenov First Moscow State Medical University (Sechenov University)

Email: aisha27_sum@mail.ru
ORCID iD: 0009-0009-8664-3536
SPIN-code: 5384-8862
Russian Federation, Moscow

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