Cytodenic characteristics of patients with brain tumors under treatment by verapamilum and ketamine in vitro

T V Fedoronchuk; Федорончук Т В; S P Syatkin; Сяткин С П; V A Frolov; Фролов Виктор Алексеевич; N Ya Gridina; Гридина Н Я; I V Boltina; Болтина И В

Cytodenic characteristics of patients with brain tumors under treatment by verapamilum and ketamine in vitro

Authors: Fedoronchuk TV¹, Syatkin SP¹, Frolov VA¹, Gridina NY.², Boltina IV³
Affiliations:
1. Russian Peoples' Friendship University
2. State Institution Institute of Neurosurgery NAMS of Ukraine
3. L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine
Issue: No 3 (2012)
Pages: 5-11
Section: Articles
URL: https://ogarev-online.ru/2313-0245/article/view/338205
ID: 338205

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Abstract

There are results of analyzing of cytogenetic characteristics of patients with brain tumors under treatment by Verapamilum and Ketamine in vitro. Under the Verapamilum action it was shown sure decreasing of the chromosome aberrations frequencies just like decreasing of the aneuploid and polyploid cells quantity in patient's malignant tumors. It also was shown the substantial reduction in aneuploid cells number among tests of patients with malignant tumors under Ketamine exposure. Patients with benign or malignant tumors had the very lowest magnitudes of multyaberratic cells amount and of the extent of aberratic cell injury under the Verapamilum influence.

Keywords

Ketamine, Verapamilum, chromosome aberrations, aneuploid and polyploid cells, brain tumors

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Cytodenic characteristics of patients with brain tumors under treatment by verapamilum and ketamine in vitro

Full Text

Abstract

Keywords

About the authors

T V Fedoronchuk

S P Syatkin

V A Frolov

N Ya Gridina

I V Boltina

Supplementary files