Morphological changes of the mucous membrane of small intestines of the experimental animals at the chronic alcoholic intoxication

The digestive path is subjected to ethanol influence at a chronic alcoholic intoxication. The influence of different terms of an alcoholic intoxication on morphological characteristics of small intestines has been investigated. In 2 months after the beginning of taking alcohol in the following indicators increased: fiber height, the volume of enterocyte kernels, specific quantity of mitoses in basal layer of mucous small intestines. In 6 months the decrease of mitotic sharing cages was observed, at the same time the volume of enterocyte kernels both in fiber and in crypta increased. Thus, there is a decrease in regenerative ability of small intestine, mucous membrane of a in a tandem with the increase of functional activity of this department of a digestive path.

alcoholic intoxication, small intestines, enterocyte