Participation of various populations lymphocytes in formation of protection from meningococcosis

O V Kotelnikova; Котельникова О В; E J Drozzina; Дрожжина Е Ю; O M Volpina; Вольпина О М; D O Koroev; Короев Д О; M P Filatova; Филатова М П; A P Alliluev; Аллилуев А П

Participation of various populations lymphocytes in formation of protection from meningococcosis

Authors: Kotelnikova OV¹, Drozzina EJ¹, Volpina OM¹, Koroev DO¹, Filatova MP¹, Alliluev AP²
Affiliations:
1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
2. Peoples' Friendship University of Russia
Issue: No 2 (2010)
Pages: 10-16
Section: Articles
URL: https://ogarev-online.ru/2313-0245/article/view/337683
ID: 337683

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Abstract

Immunization of mice by synthetic peptides fragments of meningococcus external membrane fibers caused the expressed protection of animals against infection caused by live virulent meningococcus culture serogroup A, B and C. There are leading part T-lymphocytes in protection of mice from this infection here. The analysis of T-cellular populations by means of a method flowing cytophluorometrics has shown increase CD4+ and CD8+ lymphocytes without change of parity CD4+/CD8+. The increase in number of these lymphocytes occurred in late terms after immunization of mice.

Keywords

immunization, meningococcus serogroup A, B and C, T-lymphocytes

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Participation of various populations lymphocytes in formation of protection from meningococcosis

Full Text

Abstract

Keywords

About the authors

O V Kotelnikova

E J Drozzina

O M Volpina

D O Koroev

M P Filatova

A P Alliluev

Supplementary files