Mathematical modeling of the kidney function in children with tubulointerstitial lesions

Abstract

Among 224 examined children with tubulointerstitial nephritis (TIN). Mathematical modeling of the kidney function condition was carried out by the method of a SMA. The impairment of the kidney function in all patients occurred due to its tubular component that manifested itself in the impaired function of proximal and distal tubule. The SMA has confirmed the primary impairment of tubular functions. The designed weight factors and integral parameters reflected the tubular dysfunction.