Effect of pentoxifylline on rheology blood in rheumatoid arthritis with systemic manifestation

N A Vinogradova; Виноградова Наталья Александровна; A A Vinogradov; Виноградов А А; N V Emanuylova; Емануйлова Н В

Effect of pentoxifylline on rheology blood in rheumatoid arthritis with systemic manifestation

Authors: Vinogradova NA¹, Vinogradov AA¹, Emanuylova NV¹
Affiliations:
1. Yaroslavl State Medical Academy
Issue: No 4 (2010)
Pages: 182-184
Section: Articles
URL: https://ogarev-online.ru/2313-0245/article/view/337443
ID: 337443

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Abstract

In people with rheumatoid arthritis with systemic manifestations were found significant changes in hemorheological profile, including increasing the viscosity of whole blood, plasma viscosity, erythrocyte aggregation and deformability. This was combined with reduced transport capacity of blood. A single infusion of pentoxifylline (100 mg) was accompanied by a positive shift of the rheological characteristics of blood, including red blood cell deformability and aggregation.

Keywords

rheumatoid arthritis, blood viscosity, plasma viscosity, deformability, aggregation, erythrocytes, pentoxifylline

About the authors

N A Vinogradova

Yaroslavl State Medical Academy

Кафедра пропедевтики внутренних болезней; Ярославская государственная медицинская академия; Yaroslavl State Medical Academy

A A Vinogradov

Yaroslavl State Medical Academy

N V Emanuylova

Yaroslavl State Medical Academy

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