Laser techniques in the analysis of solutions synthetic peptides

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Abstract

The search for new drugs based on protein/peptide compounds is associated with the development of methods for quality control and standardization of pharmaceutical preparations. The physicochemical properties of solutions of peptides synthesized by the method of dynamic light scattering (DLS) are discussed. The dispersion distribution of peptide molecules in size and the number are described. The results can be used for qualitative evaluation of peptide drug solutions.

About the authors

E V Uspenskaya

Peoples’ Friendship University of Russia

Email: uspenskaya75@mail.ru
Department of Pharmaceutical and Toxicological Chemistry

T V Pleteneva

Peoples’ Friendship University of Russia

Email: tvplet@mail.ru
Department of Pharmaceutical and Toxicological Chemistry

T A Golubtsova

Testing Laboratory «Pharmconstant»

Email: tania.golubtsova@yandex.ru

A Yu Skripnikov

Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences

Email: a.skripnikov@gmail.com

A V Syroeshkin

Institute of Applied Geophysics

Email: livmatter@mail.ru

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