在出生后第一年接受手术的患有肾积水的儿童接受治疗的长期结果。系统综述

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现实性。肾盂输尿管连接部梗阻是儿童肾积水的最常见原因。

该研究的目的是搜索和分析1998年至2021年期间关于出生后第一年肾积水的手术治疗及其长期结果的现有文献。

材料和方法。在PubMed、Web of Science、Scopus、Google Scholar和Elibrary数据库中进行文献检索。使用了以下关键词来搜索资料：“congenital hydronephrosis”/“врожденный гидронефроз”（先天性肾积水）、“severe hydronephrosis”/“тяжелая степень гидронефроза”（重度肾积水）、“operative treatment”/“оперативное лечение” （手术治疗）、“uretero-pelvic junction obstruction infant”（婴儿肾盂输尿管连接部 梗阻）、“children, neonatal”（儿童的、新生儿的）、“infancy”(婴儿期)、 “обструкция пиелоуретрального сегмента”（肾盂输尿管连接部梗阻）、“дети 1 года жизни”（1岁儿童）。该综述包括5篇符合PRISMA报告标准并受分析的全文文章。

结果。根据选定的出版物，患者总数为355人。只有两位作者的研究中描述了产前筛查。手术时儿童的平均年龄为4.5个月（1-6个月）。所有作者都指出，在出生后第一年进行肾盂成形术时，肾实质厚度明显增加。在一年内，这些数值平均增加了1.5倍。肾盂的大小减少了50-67%。放射性同位素闪烁照相法的数据是可变的。在长期中，所有出版物中都观察到肾功能的改善。

结论。一项系统综述显示在患有先天性肾积水的情况下对出生后第一年接受手术的儿童进行肾盂成形术的长期结果。观察到，手术后肾盂缩小和肾实质的厚度增加。这是恢复肾脏功能的一个优势。然而，在我们能接触的文献中并没有统一的算法以预测肾实质的恢复。对肾实质功能更准确的评估，需要通过大量病例的前瞻性随机长期试验来证实。

作者简介

Anastasia A. Bebenina

Pirogov Russian National Research Medical University

Email: anastasia.bebenina@yandex.ru
ORCID iD: 0000-0002-8390-822X
SPIN 代码: 5298-7083

postgraduate student

俄罗斯联邦, Moscow

Olga G. Mokrushina

Pirogov Russian National Research Medical University; Filatov Children’s Hospital

Email: mokrushina@yandex.ru
ORCID iD: 0000-0003-4444-6103
SPIN 代码: 5998-7470

Dr. Sci. (Med.), MD, Professor of the Department of Pediatric Surgery

俄罗斯联邦, Moscow; Moscow

Marina V. Levitskaya

Filatov Children’s Hospital

Email: urolog@neosurg.ru
ORCID iD: 0000-0002-9838-9493
SPIN 代码: 2609-2557

Cand. Sci. (Med.)

俄罗斯联邦, Moscow

Vasily S. Shumikhin

Pirogov Russian National Research Medical University; Filatov Children’s Hospital

Email: vashou@gmail.com
ORCID iD: 0000-0001-9477-8785
SPIN 代码: 6405-8928

Cand. Sci. (Med.)

俄罗斯联邦, Moscow; Moscow

Nadezhda O. Erokhina

Filatov Children’s Hospital

Email: nadegdaerokhina@yandex.ru
ORCID iD: 0000-0003-0519-7220
SPIN 代码: 5169-3443
俄罗斯联邦, Moscow

Anzhelika E. Agavelyan

Pirogov Russian National Research Medical University

编辑信件的主要联系方式.
Email: lika.lk@mail.ru
ORCID iD: 0009-0005-5361-8589

student

俄罗斯联邦, Moscow

参考

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补充文件

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1. JATS XML
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2. Fig. 1. Stages of the study according to the PRISMA criteria

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3. Fig. 2. Dynamics of kidney parameters 1 year after surgery

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4. Fig. 3. Comparison of classification systems for hydronephrosis [6]

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