Surgical treatment of a newborn in critical condition with intrapericardiac teratoma: a case report

Cover Page

Cite item

Full Text

Abstract

This article presents a clinical case of the successful surgical treatment of a newborn with intrapericardial teratoma, which was initially diagnosed in the postnatal period, complicated by multiple organ failure, including severe cardio-respiratory disorders and acute renal damage. The systematized results of clinical, electrophysiological, radiation, and morphological diagnostics during the initial examination and at the stages of supervision of the newborn are reported. On the nineteenth day of life, significant multidisciplinary cooperation was implemented to perform a radical surgical intervention to remove the intrapericardial teratoma in a patient in critical condition due to heart compression and intrathoracic tension syndrome, which determined the needed prosthetics for vital functions. Two months after the operation, the efficiency of the intervention and complex therapy was confirmed by the direct results and data of the infant’s examination. The organizational aspects provided newborns with emergency multidisciplinary specialized medical care.

About the authors

Yurii I. Kucherov

Speranskiy Children’s Clinical Hospital; Pirogov Russian National Research Medical University

Email: ykucherov@mail.ru
ORCID iD: 0000-0001-7189-373X
SPIN-code: 4391-4472

Dr. Sci. (Med.), Professor

Russian Federation, 29 Shmitovskii proezd, Мoscow, 123317; Moscow

Yulia V. Zhirkova

Speranskiy Children’s Clinical Hospital; Pirogov Russian National Research Medical University

Email: nomail@mail.ru
ORCID iD: 0000-0001-7861-6778
SPIN-code: 5560-6679

Dr. Sci. (Med.), Professor

Russian Federation, 29 Shmitovskii proezd, Мoscow, 123317; Moscow

Marat V. Tarayan

M.F. Vladimirskii Moscow Regional Scientific Research Institute

Email: nomail@mail.ru
ORCID iD: 0000-0003-4620-1679

Cand. Sci (Med.)

Russian Federation, 129110, Moscow, st. Shchepkina 61/2, building 1

Maria V. Samorokovskaya

Speranskiy Children’s Clinical Hospital; Pirogov Russian National Research Medical University

Email: masha-sam94@mail.ru
ORCID iD: 0000-0002-8897-5886

pediatric surgeon

Russian Federation, 29 Shmitovskii proezd, Мoscow, 123317; 1 Ostrovityanova st., 117997, Moscow

LIliia V. Shvets

Speranskiy Children’s Clinical Hospital

Author for correspondence.
Email: lilishv@gmail.com
ORCID iD: 0000-0002-1317-4478

pediatric surgeon

Russian Federation, 29, Shmitovskii proezd, Мoscow, 123317

References

  1. Azzakhmam M, Kessab A, Malihy A, et al. Intracardiac Teratoma in an Infant: Report of a New Case and Literature Review. Case Rep Pathol. 2018;2018. doi: 10.1155/2018/6805234
  2. Joёl VJ. Ein Teratom auf der Arteria pulmonalis innerhalb des Herzbeutels. Anatomie. 1890;122:381. (In German.)
  3. Devlieger A, Hindryckx T, Van Mieghem, et al. Therapy for foetal pericardial tumours: Survival following in utero Shunting, and literature review. Fetal Diagn Ther. 2009;25(4):407–412. doi: 10.1159/000236156
  4. Avondo S, Andreis A, Casula M, Imazio M. Update on diagnosis and management of neoplastic pericardial disease. Medicine Expert Review of Cardiovascular Therapy. 2020;18(9):615–623. doi: 10.1080/14779072.2020.1811087
  5. Uzun O, Wilson DG, Vujanic GM, et al. Cardiac tumours in children. Orphanet J Rare Dis. 2007;2:11. doi: 10.1186/1750-1172-2-11
  6. Kim E, Bae TS, Kwon Y, et al. Primary malignant teratoma with a primitive neuroectodermal tumor componentin thyroid gland: a case report. J Korean Med. Sci. 2007;22(3):568–571. doi: 10.3346/jkms.2007.22.3.568
  7. Sagojan GB, Kachanov DJu, Grachev NS, et al. Sluchai vrozhdennoi nezreloi teratomy golovy i shei. Voprosy gematologii/onkologii i immunopatologii v pediatrii. 2017:16(3)73–80. doi: 10.24287/1726-1708-2017-16-3-73-80
  8. Morozov DA, Pimenova ES, Dvoryakovsky IV, Talalaev AG. Thyroid teratomas in newborn babies. Russian Journal of Pediatric Surgery. 2014;18(5):33–36.
  9. Tao TY, Yahyavi-Firouz-Abadi N, Singh GK, Bhalla S. Pediatric cardiac tumors: clinical and imaging features. Radiographics. 2014;34(4):1031–1046. doi: 10.1148/rg.344135163
  10. Singh VM, VSM BSK. A rare case of intrapericardial teratoma presenting as a mediastinal mass in an infant. MJAFI. 2013;71(1):S49–S51. doi: 10.1016/j.mjafi.2013.01.006
  11. Kucherov YuI, Zhirkova YuV, Tarayan MV, et al. A case of successful surgical treatment of intrapericardial teratoma in a newborn baby. Russian Journal of Pediatric Surgery. 2016;20(1):53–55. doi: 10.18821/1560-9510-2016-20-1-53-55
  12. Project Inner Eye. Medical Imaging AI to Empower Clinicians [Internet] Available: https://www.microsoft.com/en-us/research/project/medical-image-analysis/
  13. Rychik J, Khalek N, J Gaynor W, et al. Fetal intrapericardial teratoma: natural history and management including successful in utero surgery. Am J Obstet Gynecol. 2016;215(6):780.e1–780.e7. doi: 10.1016/j.ajog.2016.08.010
  14. Nassr A, Shazly S, Morris S, et al. Prenatal management of fetal intrapericardial teratoma: a systematic review. Prenat Diagn. 2017;37(9):849–863. doi: 10.1002/pd.5113
  15. Hawkins RB, Rosenberger LH, Swanson JC, et al. Excision of an intrapericardial immature teratoma in a 26-week premature neonate. J Pediatr Surg Case Rep. 2016;10:29–31. doi: 10.1016/j.epsc.2016.04.026
  16. Moch H, Cubilla AL, Humphrey PA, et al. The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. Eur Urol. 2016;70(1):93-105. doi: 10.1016/j.eururo.2016.02.029. Epub 2016 Feb 28.
  17. Schneider DT, Calaminus G, et al. Epidemiologic Analysis of 1,442 Children and Adolescents Registered in the German Germ Cell Tumor Protocols. Pediatr Blood Cancer. 2004;42(2):169–175. doi: 10.1002/pbc.10321.

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. A CT scan of a newborn. The markings indicate the pathological formation of the mediastinum

Download (104KB)
3. Fig. 2. Surgery to remove the tumor: a — the stage of sternotomy, pericardiotomy; b — isolated intrapericardial neoplasm; c — the stage of isolating neoplasms from the structures of the heart; d—macropreparate of the removed neoplasm

Download (405KB)

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).