Email this article Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age
- Authors: Mikhaylin E.S.1,2,3, Ivanova L.A.1,2, Shilo M.M.2, Berlev I.V.2
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Affiliations:
- Maternity Hospital №10
- Mechnikov North-Western State Medical University
- People’s Friendship University of Russia
- Issue: Vol 22, No 6 (2020)
- Pages: 90-92
- Section: CLINICAL CASE
- URL: https://ogarev-online.ru/2079-5831/article/view/34862
- DOI: https://doi.org/10.26442/20795696.2020.6.200407
- ID: 34862
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Abstract
The article presents a personal observation of the course of pregnancy and childbirth in a patient with a typical form of gonadal dysgenesis (Shereshevsky–Turner syndrome, karyotype 45,X0/46,XY in the ratio of clones 1:1). The diagnosis was established at 12 years of age during an examination for growth retardation and lack of signs of puberty. Given the presence of a 46,XY clone in the karyotype, a high risk of malignization of dysgenetic gonads, laparoscopy and gonadectomy were performed at 12 years of age. Pregnancy occurred after preparation of the endometrium with estrogens and progestogens, as a result of the first in vitro fertilization attempt with a donor egg and her husband’s sperm, occurred against the background of hormonal support with the threat of termination of pregnancy and hypercoagulation. At 34 weeks, there was a premature detachment of placenta, in connection with which she was delivered by cesarean section.
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##article.viewOnOriginalSite##About the authors
Evgeny S. Mikhaylin
Maternity Hospital №10; Mechnikov North-Western State Medical University; People’s Friendship University of Russia
Author for correspondence.
Email: mihailin@mail.ru
ORCID iD: 0000-0001-5965-3020
SPIN-code: 8510-7710
Cand. Sci. (Med.)
Russian Federation, Saint Petersburg; 41, Kirochnaya street, Saint-Petersburg, 191015; 6, Miklukho-Maklaya street, Moscow, 117198Lada A. Ivanova
Maternity Hospital №10; Mechnikov North-Western State Medical University
Email: roddom10@zdrav.spb.ru
ORCID iD: 0000-0002-3391-6694
Cand. Sci. (Med.)
Russian Federation, Saint Petersburg; 41, Kirochnaya street, Saint-Petersburg, 191015Mariya M. Shilo
Mechnikov North-Western State Medical University
Email: roddom10@zdrav.spb.ru
ORCID iD: 0000-0002-7558-8342
SPIN-code: 8358-5911
Clin. Resident
Russian Federation, 41, Kirochnaya street, Saint-Petersburg, 191015Igor V. Berlev
Mechnikov North-Western State Medical University
Email: roddom10@zdrav.spb.ru
D. Sci. (Med.), Prof.
Russian Federation, 41, Kirochnaya street, Saint-Petersburg, 191015References
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