Microelectrode recording of neuronal activity in the surgery for Parkinson’s disease
- Authors: Nizametdinova D.M.1, Tyurnikov V.M.1, Fedorenko I.I.1, Gushcha A.O.1, Illarioshkin S.N.1
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Affiliations:
- Research Center of Neurology
- Issue: Vol 10, No 2 (2016)
- Pages: 42-45
- Section: Technologies
- URL: https://ogarev-online.ru/2075-5473/article/view/124678
- DOI: https://doi.org/10.17816/psaic60
- ID: 124678
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Abstract
Microelectrode recording of neuronal activity is a modern and safe tool for neurophysiological mapping of subcortical brain structures that serve as targets for stereotactic functional neurosurgery. The article discusses the main technical and clinical aspects of this method and focuses on Parkinson’s disease, a classical object of functional neurosurgery. Microelectrode analysis improves the accuracy of electrode positioning and the effectiveness of surgical neuromodulation in Parkinson’s disease, enables investigation of the pathophysiological features of extrapyramidal disorders, mechanisms of action of drugs and various functional neurosurgery techniques, and also facilitates the search for new potential targets for deep brain stimulation.
About the authors
D. M. Nizametdinova
Research Center of Neurology
Author for correspondence.
Email: dinara.dinara@mail.ru
Russian Federation, Moscow
Vladimir M. Tyurnikov
Research Center of Neurology
Email: dinara.dinara@mail.ru
Russian Federation, Moscow
I. I. Fedorenko
Research Center of Neurology
Email: dinara.dinara@mail.ru
Russian Federation, Moscow
Artem O. Gushcha
Research Center of Neurology
Email: dinara.dinara@mail.ru
Russian Federation, Moscow
Sergey N. Illarioshkin
Research Center of Neurology
Email: dinara.dinara@mail.ru
ORCID iD: 0000-0002-2704-6282
D. Sci. (Med.), Prof., Corr. Member of the Russian Academy of Sciences, Deputy Director, Head, Department for brain research
Russian Federation, MoscowReferences
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