A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease
- Authors: Thiruvuru I.1, Hazeena P.1, Ramesh R.1, Shanmugam S.1, Avadhani D.1
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Affiliations:
- Sri Ramachandra Institute of Higher Education and Research
- Issue: Vol 18, No 2 (2024)
- Pages: 95-99
- Section: Clinical analysis
- URL: https://ogarev-online.ru/2075-5473/article/view/262429
- DOI: https://doi.org/10.17816/ACEN.977
- ID: 262429
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Abstract
Creutzfeldt–Jakob Disease (CJD) is a rare and rapidly progressive condition. A 54-year-old professor initially presented with insidious, progressive visual symptoms. Imaging suggested post-infectious encephalitis, but symptoms progressed to ataxia, coordination difficulties, and cognitive decline. Repeat MRI revealed findings consistent with CJD, supported by clinical and electrophysiological evidence. Though 14-3-3 protein in CSF was inconclusive, Heidenhain variant CJD was strongly suspected. Isolated visual symptoms progressing rapidly alongside ataxia and dementia prompt suspicion of this variant. Clinical examination, neuroimaging, and EEG play crucial roles in the diagnosis.
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##article.viewOnOriginalSite##About the authors
Ishwarya Thiruvuru
Sri Ramachandra Institute of Higher Education and Research
Email: madhandhoni@gmail.com
ORCID iD: 0009-0003-7261-5151
MD, senior resident, Department of neurology, Sri Ramachandra Institute of Higher Education and Research
India, Porur, ChennaiPhilo Hazeena
Sri Ramachandra Institute of Higher Education and Research
Email: philohazeena@yahoo.co.in
ORCID iD: 0000-0001-6221-431X
MD (DM Neuro), associate professor, Department of neurology, Sri Ramachandra Institute of Higher Education and Research
India, Porur, ChennaiRithvik Ramesh
Sri Ramachandra Institute of Higher Education and Research
Author for correspondence.
Email: rithvy@gmail.com
ORCID iD: 0000-0002-4142-637X
MD (DM Neuro), assistant professor, Department of neurology, Sri Ramachandra Institute of Higher Education and Research
India, Porur, ChennaiSundar Shanmugam
Sri Ramachandra Institute of Higher Education and Research
Email: drradnus@gmail.com
ORCID iD: 0000-0002-6580-9017
MD (DM Neuro), Professor, Head, Department of neurology, Sri Ramachandra Institute of Higher Education and Research
India, Porur, ChennaiDeepa Avadhani
Sri Ramachandra Institute of Higher Education and Research
Email: doctordeepaavadhani@gmail.com
ORCID iD: 0009-0004-0991-9563
MD (DM Neuro), Assistant professor, Department of neurology, Sri Ramachandra Institute of Higher Education and Research
India, Porur, ChennaiReferences
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