Neurological debut of non-Hodgkin’s lymphoma: the complexity of diagnosis
- Authors: Magzhanov R.V.1, Bakhtiyarova K.Z.1, Tunik V.F.2, Dolganyuk V.K.2, Galliamova N.A.2, Zakirova E.N.2, Pervushina E.V.2
-
Affiliations:
- Bashkir State Medical University
- G.G. Kuvatov Republican Clinical Hospital
- Issue: Vol 8, No 2 (2014)
- Pages: 37-40
- Section: Clinical analysis
- URL: https://ogarev-online.ru/2075-5473/article/view/124635
- DOI: https://doi.org/10.17816/psaic182
- ID: 124635
Cite item
Full Text
Abstract
A rare case of system non-Hodgkin’s lymphoma manifested with oculomotor abnormalities is presented in the paper. In the patient examined, initial symptoms were diplopia and restriction of the lateral eye movements; these symptoms appeared on the background of the intense headaches. The death resulted from the acute cardio-pulmonary failure. On postmortem study, B-cell lymphoma of multiple localizations, including the central nervous system, heart, lymph nodes, spleen and liver, was found.
About the authors
R. V. Magzhanov
Bashkir State Medical University
Email: bsmu-neuro@yandex.ru
Russian Federation, Ufa
K. Z. Bakhtiyarova
Bashkir State Medical University
Email: bsmu-neuro@yandex.ru
Russian Federation, Ufa
V. F. Tunik
G.G. Kuvatov Republican Clinical Hospital
Email: bsmu-neuro@yandex.ru
Russian Federation, Ufa
V. K. Dolganyuk
G.G. Kuvatov Republican Clinical Hospital
Email: bsmu-neuro@yandex.ru
Russian Federation, Ufa
N. A. Galliamova
G.G. Kuvatov Republican Clinical Hospital
Email: bsmu-neuro@yandex.ru
Russian Federation, Ufa
E. N. Zakirova
G.G. Kuvatov Republican Clinical Hospital
Email: bsmu-neuro@yandex.ru
Russian Federation, Ufa
E. V. Pervushina
G.G. Kuvatov Republican Clinical Hospital
Author for correspondence.
Email: bsmu-neuro@yandex.ru
Russian Federation, Ufa
References
- Гематология: руководство для врачей (под ред. Н.Н. Мамаева, С.И. Рябова). СПб.: СпецЛит, 2008.
- Гончарова О.В., Липатов О.Н. Оценка распространенности неходжкинских лимфом. Мед. Вестн. Башкортостана 2009; 1: 25–28.
- Akaza M., Tsunemi T., Sanjo N. et al. Malignant lymphoma presented as left trigeminal neuralgia. Rinsho Shinkeigaku 2009; 49: 432–436.
- Arai A., Taomoto K., Yokoyama M. et al. A case of CNS metastasis from gastric MALT lymphoma. No Shinkei Geka 2009; 37: 1235–1240.
- Hunt K.E., Reichard K.K. Diffuse large B-cell lymphoma. Arch. Pathol. Lab. Med. 2008; 132; 118–124.
- Kawano N., Ochiai H., Yoshida S. et al. Clinical features and treatment outcomes of isolated secondary central nervous system lymphomas in Miyazaki Prefecture. Int. J. Clin. Oncol. 2012; 17: 336–340.
- Kobayashi Z., Tsuchiya K., Machida A. et al. Metastatic CNS lymphoma presenting with periventricular dissemination – MRI and neuropathological findings in an autopsy case. J. Neurol. Sci. 2009; 277:109–113.
- Miranda R.N., Glantz L.K., Myint M.A. et al. Stage IE non-Hodgkin’s lymphoma involving the dura: A clinicopathologic study of five cases. Arch. Pathol. Lab. Med. 1996; 120: 254–260.
- Muzaffar S., Siddiqui M.S., Siddiqui I. et al. Central nervous system lymphomas: a histologic and immunophenotypic analysis. J. Pak. Med.Assoc. 2000; 50: 141–144.
- Ono K., Arimoto H., Wada K. et al.Multicentric involvement of non-Hodgkin’s lymphoma in the central nervous system and testis-case report. Neurol. Med. Chir. 2004; 44: 493–496.
- Sumrall A, Herrin V. Recurrent, transformed non-Hodgkin’s lymphoma presenting as chiasmal syndrome with hyperprolactinemia and hypopituitarism. J. Miss. State Med. Assoc. 2010; 51: 35–36.
Supplementary files
