Critical neurological conditions: severe toxic polyneuropathy with the development of respiratory failure and rhabdomyolysis
- 作者: Ryabinkina Y.V.1, Zakharova M.N.1, Polishchuk R.V.1, Luneva I.E.1, Pavlov E.V.1, Piradov M.A.1
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隶属关系:
- Research Center of Neurology
- 期: 卷 12, 编号 3 (2018)
- 页面: 81-85
- 栏目: Clinical analysis
- URL: https://ogarev-online.ru/2075-5473/article/view/124293
- DOI: https://doi.org/10.25692/ACEN.2018.3.11
- ID: 124293
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This is a description of the clinical case of severe toxic polyneuropathy in a 52-year-old man, caused by a confirmed exogenous intoxication with amphetamine.
The clinical picture was remarkable for muscle weakness in different muscle groups: neck, back, arms and legs, respiratory muscles; as well as for the respiratory failure (requiring mechanical ventilation), rhabdomyolysis, mild nephropathy, liver cytolysis. A differential diagnosis was made between myasthenia gravis, myopathy, amyotrophic lateral sclerosis. After a course of intensive therapy, almost complete regression of symptoms took place, as well as the improvement of electroneuromyographic pattern. Taking into account a rapid partial regression of symptoms in the course of the disease, as well as the results of a neurophysiological study, an immunochromatographic urine drug screen was performed, positive for amphetamine. This clinical case demonstrates "rare" complications of amphetamine use to be kept in mind during a diagnostic search.
作者简介
Yulia Ryabinkina
Research Center of Neurology
Email: lunevairinaneurology@gmail.com
ORCID iD: 0000-0001-8576-9983
D. Sci. (Med.), Head, Department of anesthesiology and intensive care
俄罗斯联邦, MoscowMaria Zakharova
Research Center of Neurology
Email: lunevairinaneurology@gmail.com
俄罗斯联邦, Moscow
Roman Polishchuk
Research Center of Neurology
Email: lunevairinaneurology@gmail.com
ORCID iD: 0000-0003-2850-3999
anesthesiologist-reanimatologist, neurologist, Intensive critical care department
俄罗斯联邦, 125367 Moscow, Volokolamskoye shosse, 80Irina Luneva
Research Center of Neurology
编辑信件的主要联系方式.
Email: lunevairinaneurology@gmail.com
俄罗斯联邦, Moscow
Eduard Pavlov
Research Center of Neurology
Email: lunevairinaneurology@gmail.com
俄罗斯联邦, Moscow
Mikhail Piradov
Research Center of Neurology
Email: lunevairinaneurology@gmail.com
ORCID iD: 0000-0002-6338-0392
D. Sci. (Med.), Professor, Full Member of the Russian Academy of Sciences, Director
俄罗斯联邦, Moscow参考
- [The main indicators of the drug service in the Russian Federation in 2014–2015: statistical sourcebook]. Мoscow; 2016. (In Russ.)
- Fedorov G.V. [Counteraction to illegal circulation of narcotic drugs, psychotropic substances and their precursors among minors and youth]. Vestnik Polotskogo gosudarstvennogo universiteta. Seriya D: ekonomicheskie i yuridicheskie nauki 2009; (10): 211–215. (In Russ.)
- Shanin I.A., Khan O.Yu., Petukhov A.E. [Detection of amphetamines in urine using immunochromatographic test strips]. Sudebno-meditsinskaya ekspertiza 2012; 55(4): 33–37. (In Russ.)
- Beck О., Kraft M., Moeller M.R. et al. Frontline immunochromatographic device for on-site urine testing of amphetamines: laboratory validation using authentic specimens. Ann Clin Biochem 2000; 37 (Pt. 2): 199–204. doi: 10.1258/0004563001899005. PMID: 10735364.
- Connell P.H. Clinical manifestations and treatment of amphetamine type of dependence. JAMA 1966; 196: 718–723.
- Albertson T.E., Walby W.F., Derlet R.W. Stimulant-induced pulmonary toxicity. Chest 1995; 108: 1140–1149. PMID: 7555128.
- Pothos E.N., Creese I., Hoebell B.G. Restricted eating with weight loss selectively decreases extracellular dopamine in the nucleus accumbens and alters dopamine response to amphetamine, morphine, and food intake. J Neurosci 1995; 75(10): 6640–6650. PMID: 7472425.
- Koren’ E.V., Kupriyanova T.A. [Hyperkinetic disorders (ADHD): clinical recommendations]. Мoscow; 2015. (In Russ.)
- Crisostomo E.A., Duncan P.W., Propst M. et al. Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients. Ann Neurol 1988. doi: 10.1002/ana.410230117. PMID: 3345072.
- Connell P.H. Amphetamine psychosis. Br Med J 1957; 1: 582.
- Parkes J.D., Fenton G.W. Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy. J Neurol Neurosurg Psychiatry 1973; 36: 1076–1081. PMID: 4359162.
- Albertson T.E., Derlet R.W., Van Hoozen B.E. Methamphetamine and the expanding complications of amphetamines. West J Med 1999; 170: 214–219. PMID: 10344175.
- Garwood E.R., Bekele W., McCulloch C.E. , Christine C.W. Amphetamine exposure is elevated in Parkinson's disease. Neurotoxicology 2006; 27: 1003–1006. doi: 10.1016/j.neuro.2006.03.015. PMID: 16620991.
- Curtin K., Fleckenstein A.E., Robison R.J. et al. Methamphetamine/amphetamine abuse and risk of Parkinson's disease in Utah: A population-based assessment. Drug Alcohol Depend 2015; 146: 30–38. doi: 10.1016/j.drugalcdep.2014.10.027. PMID: 25479916.
- Stafford C.R., Bogdanoff B.M., Green L., Spector H.B. Mononeuropathy multiplex as a complication of amphetamine angiitis. Neurology 1975; 25: 570–572. PMID: 165440.
- Citron B.P., Halpern M., McCarron M. et al. Necrotizing angiitis a ssociated with drug abuse. N Engl J Med 1970; 283: 1003–1011. doi: 10.1056/NEJM197011052831901. PMID: 4394271.
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