Vascular wall properties of the vertebral arteries in patients with ischemic stroke in posterior circulation

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Abstract

The aim was to assess the vascular properties of the vertebral arteries (VA) in healthy persons and to detect their possible impairments in patients with ischemic stroke in posterior circulation (PCIS) and patients with vertebrobasilar insufficiency (VBI). 39 patients with PCIS, 29 patients with VBI and 65 healthy voluntaries were included into the study. Wall thickness, systolic and diastolic diameters of the VA and the common carotid arteries were measured using ultrasonography and indexes characterizing elastic properties of vascular walls (compliance, distensibility, beta stiffness index) were calculated. As appose to the common carotid arteries wall thickness, vessel diameter and stiffness of the VA were not significantly correlated with age. This finding might be linked with the difference in the age-related remodeling processes in these arteries. Stiffness of the VA was significantly higher in patients with PSIC and VBI in comparison with healthy voluntaries, and this stiffness increase could be a risk factor for PCIS.

About the authors

A. Yu Vishnyakova

N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Email: vishau@yandex.ru
науч. сотр. НИИ цереброваскулярной патологии и инсульта 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1

V. G Lelyuk

N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

д-р мед. наук, проф., гл. науч. сотр. НИИ цереброваскулярной патологии и инсульта 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1

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