Principles of drug therapy of arterial hypertension


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Abstract

This article presents an algorithm for choosing the optimal drug for the treatment of arterial hypertension, classification of arterial hypertension, describes the main group of hypotensive drugs with the characteristic of their mechanism of action and the development of possible side effects. The authors of the article describe the hypotensive drug of the group of angiotensin II AT1 receptor blockers - candesartan (Hyposart, Akrikhin company). The article presents the results of multicenter randomized studies of candesartan in patients with arterial hypertension, nephropathy associated with diabetes mellitus and heart failure. This article presents the algorithm for choosing optimal hypotensive drug, as well as shows evidence-based information concerning efficacy and safety of the drug candesartan. Candesartan provides dose-dependent antihypertensive effect in all categories of patients with arterial hypertension and can be recommended in wide clinical use.

About the authors

V. S Zadionchenko

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: z7vladimir@bk.ru
д-р мед. наук, проф. каф. поликлинической терапии; засл. деятель науки. 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

G. G Shekhyan

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: grant.shekhyan@gmail.com
канд. мед. наук, доц. каф. поликлинической терапии 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

A. A Yalymov

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: ayalymov@gmail.com
канд. мед. наук, доц. каф. поликлинической терапии 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

A. M Shchikota

A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

Email: alexmschikota@mail.ru
канд. мед. наук, доц. каф. поликлинической терапии 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1

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