Acute kidney injury: a modern view on the problem

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Abstract

Acute kidney injury (AKI) is the term that has come to replace the concept of «acute renal failure», it is a syndrome of sharp decline in renal function, which is characterized by decreased urine output up to anuria, accumulation products of nitrogen metabolism, and the violation of water-electrolyte metabolism, and is associated with high mortality and the subsequent development of chronic renal failure. Diagnostic criteria of AKI are serum creatinine, glomerular filtration rate and the magnitude of the volume of urine output. At the base of AKI are the following groups of reasons: prerenal, renal and postrenal. The therapyshould be selected taking into account the underlying disease and the degree of severity of the AKI. To evaluate the effectiveness of AKItherapy it must be constantly monitor diuresis, creatinine, urea and electrolytes.

About the authors

M. M Batiushin

Rostov State Medical University

Email: nephr-roon@rambler.ru
д-р мед. наук, проф. каф. внутренних болезней №2, зав. нефрологическим отд-нием, ФГБОУ ВО РостГМУ 344022, Russian Federation, Rostov-on-Don, per. Nakhichevanskii, d. 29

L. I Rudenko

Rostov State Medical University

канд. мед. наук, врач-нефролог нефрологического отд-ния ФГБОУ ВО РостГМУ 344022, Russian Federation, Rostov-on-Don, per. Nakhichevanskii, d. 29

A. A Kastanayan

Rostov State Medical University

д-р мед. наук, проф., зав. каф. внутренних болезней №2 ФГБОУ ВО РостГМУ 344022, Russian Federation, Rostov-on-Don, per. Nakhichevanskii, d. 29

B. I Vorobiev

Rostov State Medical University

д-р мед. наук, проф. каф. внутренних болезней №2 ФГБОУ ВО РостГМУ 344022, Russian Federation, Rostov-on-Don, per. Nakhichevanskii, d. 29

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