Rare clinical variant of palmoplantar keratoderma
- 作者: Novikov Y.A.1, Pravdina O.V.1, Zykova E.A.1, Gamza S.R.2
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隶属关系:
- Omsk State Medical University
- Clinical Dermatovenerologic Dispensary
- 期: 卷 30, 编号 8 (2023)
- 页面: 126-128
- 栏目: Clinical case
- URL: https://ogarev-online.ru/2073-4034/article/view/275585
- DOI: https://doi.org/10.18565/pharmateca.2023.8.126-128
- ID: 275585
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详细
The article presents a clinical case of an 18-year-old patient with aquagenic keratoderma. This is a rare variant of acquired palmoplantar keratoderma, which is characterized by the appearance of dense waxy foci of white-yellow hyperkeratosis with swelling of the skin, lichenification, as well as plaques with a surface in the form of a «cobblestone pavement» after contact with water. Aquagenic keratoderma occurs in 44–80% of cases in patients with cystic fibrosis who have a homo- or heterozygous mutation δF508 in the CFTR gene responsible for regulating electrolyte transport. This clinical case is of interest to practicing dermatologists.
作者简介
Yu. Novikov
Omsk State Medical University
Email: zyk.alena@mail.ru
ORCID iD: 0000-0003-0391-5372
Department of Dermatovenereology and Cosmetology
俄罗斯联邦, OmskO. Pravdina
Omsk State Medical University
Email: zyk.alena@mail.ru
ORCID iD: 0000-0002-1804-6248
Department of Dermatovenereology and Cosmetology
俄罗斯联邦, OmskElena Zykova
Omsk State Medical University
编辑信件的主要联系方式.
Email: zyk.alena@mail.ru
ORCID iD: 0000-0002-8293-4127
Cand. Sci. (Med.), Teaching Assistant, Department of Dermatovenereology and Cosmetology
俄罗斯联邦, OmskS. Gamza
Clinical Dermatovenerologic Dispensary
Email: zyk.alena@mail.ru
ORCID iD: 0009-0005-6066-3417
俄罗斯联邦, Omsk
参考
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