A case of onychomycosis caused by the pathogen Trichophyton verrucosum in a patient with concomitant dermatological pathology

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

Background. Nail pathologies which manifest with similar clinical signs are a common clinical situation in the practice of a dermatovenerologist. The imperfection of laboratory methods for research on fungal infections, the presence of combined lesions of the nail plates with other skin changes in the patient, as well as the growth of atypical pathogens in the etiological structure of onychomycosis complicate diagnosis.

Description of a clinical case. The article presents a clinical observation of a patient with a long-term course of nail mycosis caused by Trichophyton verrucosum, combined with changes in the skin of the face, scalp and perianal area. Repeated microscopic examinations of scrapings from the nail plates showed the presence of single yeast cells and spores, while external etiotropic therapy did not lead to improvement. PCR diagnostics for fungi gave a positive result (Fungi 32.7), but the pathogen was not identified. Subsequent cultural research gave an increase in colonies of the fungus T. verrucosum.

Conclusion. The clinical case demonstrates the need for a personalized approach to patients with long-term dermatoses and reflects the pathomorphosis in the course of skin diseases, including fungal etiology. To finally diagnose nail mycosis caused by a zooanthropophilic pathogen, our patient needed a combination of several laboratory research methods.

Авторлар туралы

Anna Chasnyk

Novosibirsk State Medical University

Хат алмасуға жауапты Автор.
Email: a.chasnyk@alumni.nsu.ru
ORCID iD: 0009-0002-3663-1827
SPIN-код: 3021-1059
Scopus Author ID: 59493909000

Teaching Assistant, Department of Dermatovenereology and Cosmetology

Ресей, Novosibirsk

Olga Pozdnyakova

Novosibirsk State Medical University

Email: pozdnyakova.o.n@mail.ru
ORCID iD: 0000-0003-1389-1001
SPIN-код: 7800-7403

Dr. Sci. (Med.), Professor, Department of Dermatovenereology and Cosmetology

Ресей, Novosibirsk

Olga Nemchaninova

Novosibirsk State Medical University

Email: obnemchaninova@mail.ru
ORCID iD: 0000-0002-5961-6980
SPIN-код: 5658-9359

Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology

Ресей, Novosibirsk

Natalia Fomenko

Vector-Best

Email: fomenkon@vector-best.ru
ORCID iD: 0000-0001-6437-8959

Cand. Sci. (Biol.), Senior Researcher, PCR Laboratory

Ресей, Novosibirsk

Tatyana Kalymbetova

Vector-Best

Email: kalymbetova@vector-best.ru
ORCID iD: 0000-0002-8648-3714

Cand. Sci. (Biol.), Researcher, PCR Laboratory

Ресей, Novosibirsk

Natalia Shipilova

Vector-Best

Email: pozdnyakova.o.n@mail.ru
ORCID iD: 0000-0002-7842-4423

Teaching Assistant, Department of Fundamental Medicine

Ресей, Novosibirsk

Irina Sergeeva

Novosibirsk National Research State University

Email: i_g_sergeeva@mail.ru
ORCID iD: 0000-0003-1748-8957
SPIN-код: 4766-0410
Scopus Author ID: 57044473200

Dr. Sci. (Med.), Professor, Department of Fundamental Medicine, V. Zelman Institute of Medicine and Psychology, Director, Center for Postgraduate Medical Education

Ресей, Novosibirsk

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