Evaluation of the level of substance P in patients with ischemic stroke in the acute phase

Resumo

We compared the level of substance P in 28 patients with the acute phase of carotid ischemic stroke at day 1 and 3 of the development of the disease. The concentration of substance P in the blood serum of patients with severe stroke was higher than in the serum of patients with the mild and medium form of the disease, as well as in the control blood-serum samples. The data we obtained suggest that the peptide plays an important role during ischemic lesion of the brain.