Evaluation of the level of substance  P  in patients with ischemic stroke in the acute phase

O. A. Levashova; I. I. Kukhtevich; I. G. Zolkornyaev; N. I. Aleshina; M. F. Kuptsova

doi:10.1134/S1819712416010128

Evaluation of the level of substance P in patients with ischemic stroke in the acute phase

Authors: Levashova O.A.¹, Kukhtevich I.I.¹, Zolkornyaev I.G.¹, Aleshina N.I.¹, Kuptsova M.F.¹
Affiliations:
1. Penza Institute of Advanced Medical Education
Issue: Vol 10, No 1 (2016)
Pages: 77-79
Section: Clinical Neurochemistry
URL: https://ogarev-online.ru/1819-7124/article/view/211019
DOI: https://doi.org/10.1134/S1819712416010128
ID: 211019

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Abstract

We compared the level of substance P in 28 patients with the acute phase of carotid ischemic stroke at day 1 and 3 of the development of the disease. The concentration of substance P in the blood serum of patients with severe stroke was higher than in the serum of patients with the mild and medium form of the disease, as well as in the control blood-serum samples. The data we obtained suggest that the peptide plays an important role during ischemic lesion of the brain.