Study of the absorbent properties of alginic acid
- Authors: Zakharov А.S.1, Barishnikova M.I.1, Saf’yanov M.A.1, Vasilovsky I.N.1, Korotkova N.V.1, Sukhova А.А.1, Fomina D.I.1, Ivankina I.V.1
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Affiliations:
- Ryazan State Medical University
- Issue: Vol 28, No 6 (2025)
- Pages: 14-20
- Section: Biological chemistry
- URL: https://ogarev-online.ru/1560-9596/article/view/310590
- DOI: https://doi.org/10.29296/25877313-2025-06-02
- ID: 310590
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Abstract
Introduction.Alginicacidis a naturalheteropolysaccharide of brownalgae,consistingofresidues of mannuronicandguluronicacids.It is usedinvariousfields:medicine,foodandpharmaceuticalindustry,cosmetology,ecology,etc. Itsability to bindandretainwatertoformhydrogels is usedin the development of newtechnologiesandmaterials. The structure of thiscompoundisinterestingfrom the point of view of studyingitsabsorbentpropertiesinrelationtosubstances of variouscompositionandstructure.
Material and methods.thestudypresentsvariousmethods for determiningsolutionconcentrationsbasedonphotocolorimetricandspectrophotometricanalysis.Thefollowing compounds wereselectedasexperimentalcompoundsfor the study of absorbentactivity: anions–nitrite,sulfate,iodide;metalcations–calciumandiron(III);protein–glutathione;organicdyes–methyleneblueandmethylorange.
Results.during the study, it turned out thatalginicacidcanabsorb the followingcompounds:nitriteanions-by90.4%,sulfateanions–by71.8%,iodideanions–by28.34%,calciumcations–by58.06%,iron(III)cations–by75.41%,protein–by48.33%,methyleneblue–by 84.22%andmethylorange–by83.72%. The authorssuggestthat the specificabsorbingactivity of alginicacidcan be explained by the followingproperties: alginicacidbindsmetalionsdue to the content of carboxylgroupsand a change in the gelstructureduringswelling; absorption of proteins is caused by electrostaticinteractionwithalginicacidandcompetitionwithmetalcationsforbindingtocarboxylgroups;absorption of anionscanbeassociatedwithelectrostaticinteractionwithcarboxylgroups.
Conclusions. alginic acid has a pronounced absorbent ability in relation to a wide range of compounds of various chemical nature. This feature makes alginic acid a compound suitable for use in filtration and dialysis systems for various purposes, including medical ones.
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##article.viewOnOriginalSite##About the authors
А. S. Zakharov
Ryazan State Medical University
Author for correspondence.
Email: AlexanderZakharov2019@yandex.ru
ORCID iD: 0000-0002-4004-7474
SPIN-code: 4906-9088
Assistant of the Department of Biological Chemistry
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026M. I. Barishnikova
Ryazan State Medical University
Email: masha.bari04@gmail.com
ORCID iD: 0009-0004-0407-6536
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026M. A. Saf’yanov
Ryazan State Medical University
Email: bellkoks@yandex.ru
ORCID iD: 0009-0008-3895-0171
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026I. N. Vasilovsky
Ryazan State Medical University
Email: vania_vania_2018@list.ru
ORCID iD: 0009-0005-0294-4990
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026N. V. Korotkova
Ryazan State Medical University
Email: fnv8@yandex.ru
ORCID iD: 0000-0001-7974-2450
SPIN-code: 3651-3813
Ph.D. (Med.), Associate Professor, Docent of the Department of Biological Chemistry
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026А. А. Sukhova
Ryazan State Medical University
Email: rrraaa724@gmail.com
ORCID iD: 0009-0006-5482-6969
Resident
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026D. I. Fomina
Ryazan State Medical University
Email: fnv8@yandex.ru
ORCID iD: 0009-0008-5532-6303
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026I. V. Ivankina
Ryazan State Medical University
Email: ira.ivankina.02@mail.ru
ORCID iD: 0009-0000-6789-8853
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026References
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