Stevens-Johnson syndrome


Cite item

Full Text

Abstract

The literature review of the epidemiology, etiology and pathogenesis, clinical presentation and diagnosis of the syndrome of Stevens-Johnson severe life-threatening disease characterized by extensive lesions of the skin and mucous membranes, fever and bone and muscle aches, often induced by medication is presented. A review on the methods of treatment and prevention of this disease is presented. The clinical case of patient with the syndrome of Stevens-Johnson is described. The successful treatment of Syndrome Stevens-Johnson with high-dose systemic glucocorticoids was performed.

About the authors

O. Yu Olisova

I.M. Sechenov First Moscow State Medical University

Department of Skin and Venereal Diseases n.a. V.A. Rakhmanov Moscow, 119991, Russian Federation

O. V Grabovskaya

I.M. Sechenov First Moscow State Medical University

Department of Skin and Venereal Diseases n.a. V.A. Rakhmanov Moscow, 119991, Russian Federation

N. P Teplyuk

I.M. Sechenov First Moscow State Medical University

Department of Skin and Venereal Diseases n.a. V.A. Rakhmanov Moscow, 119991, Russian Federation

A. A Lepekhova

I.M. Sechenov First Moscow State Medical University

Department of Skin and Venereal Diseases n.a. V.A. Rakhmanov Moscow, 119991, Russian Federation

D. V Ignatiev

I.M. Sechenov First Moscow State Medical University

Department of Skin and Venereal Diseases n.a. V.A. Rakhmanov Moscow, 119991, Russian Federation

Kseniya V. Ignatieva

I.M. Sechenov First Moscow State Medical University

Email: deleraugo@gmail.com
clinical ordinator of Department of Skin and Venereal Diseases of I.M. Setchenov First Moscow State Medical University Moscow, 119991, Russian Federation

References

  1. Заславский Д.В., Горланов И.А., Самцов А.В., Хайрутдинов В.Р. Федеральные клинические рекомендации по ведению больных cиндромом Стивенса-Джонсона/токсическим эпидермальным некролизом. М.: Российское общество дерматовенерологов и косметологов; 2013.
  2. Harr T., French L.E. Toxic epidermal necrolysis and Stevens-Johnson syndrome. Orphanet. J. Rare Dis. 2010; 5: 39-50. doi: 10.1186/1750-1172-5-39.
  3. Miliszewski M.A., Kirchhof M.G., Sikora S., Papp A., Dutz J.P. Stevens-Johnson syndrome and toxic epidermal necrolysis: an analysis of triggers and implications for improving prevention. Am. J. Med. 2010; 123(3): 22-40.
  4. Lu N., Rai S.K., Terkeltaub R., Kim S.C., Menendez M.E., Choi H.K. Racial disparities in the risk of Stevens-Johnson syndrome and toxic epidermal necrolysis as urate-lowering drug adverse events in the United States. Semin. Arthritis. Rheum. 2016. pii: S0049-0172(16)30004-X. doi: 10.1016/j.semarthrit.2016.03.014.
  5. Chung W.H., Hung S.I. Genetic markers and danger signals in Stevens-Johnson syndrome and toxic epidermal necrolysis. Allergol. Inter. 2010; 59(4): 325-32.
  6. French L.E. Toxic epidermal necrolysis and Stevens-Johnson syndrome: our current understanding. Allergol. Inter. 2006; 55(1): 9-16.
  7. Ho H.H.F. Diagnosis and management of Stevens-Johnson Syndrome and toxic epidermal necrolysis. HongKong Med. Diary. 2008; 13(10): 17-20.
  8. Kardaun S.H., Jonkman M.F. Dexamethasone pulse therapy for Stevens-Johnson Syndrome/toxic epidermal necrolysis. Acta Derm. Venereol. 2007; 87(2): 144-8.
  9. Momin S.B. Review of intravenous immunoglobulin in the treatment of Stevens-Johnson Syndrome and toxic epidermal necrolysis. J. Clin. Aesthet. Dermatol. 2009; 2(2): 51-8.
  10. Григорьев Д.В. Многоформная экссудативная эритема, синдром Стивенса-Джонсона и синдром Лайелла - современная трактовка проблемы. Русский медицинский журнал. Дерматология. 2013; 21(22): 1073-83. http://www.rmj.ru/articles/dermatologiya/Mnogoformnaya_ekssudativnaya_eritema_sindrom_StivensaDghonsona_i_sindrom_Layella_sovremennaya_traktovka_problemy/#ixzz4G5NNRx8f

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2016 Eco-Vector


 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).