The reaction of amidoximes with carboxylic acids or their esters under high-pressure conditions

S. V. Baikov; G. A. Stashina; E. I. Chernoburova; V. B. Krylov; I. V. Zavarzin; E. R. Kofanov

doi:10.1007/s11172-019-2391-9

The reaction of amidoximes with carboxylic acids or their esters under high-pressure conditions

作者: Baikov S.V.¹, Stashina G.A.², Chernoburova E.I.², Krylov V.B.², Zavarzin I.V.², Kofanov E.R.³
隶属关系:
1. K. D. Ushinsky Yaroslavl State Pedagogical University
2. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
3. Yaroslavl State Technical University
期: 卷 68, 编号 2 (2019)
页面: 347-350
栏目: Full Articles
URL: https://ogarev-online.ru/1066-5285/article/view/243252
DOI: https://doi.org/10.1007/s11172-019-2391-9
ID: 243252

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详细

3,5-Disubstituted 1,2,4-oxadiazoles were synthesized by the reaction of amidoximes with carboxylic acids or their esters under high-pressure conditions (10 kbar). The reaction proceeds without the use of other reagents or catalysts. Both aliphatic and aromatic carboxylic acids undergo this reaction. The obtained 1,2,4-oxadiazoles possess high fungicidal activity.