Rearrangement in the systems ethyl bromopyruvate-1-(cyclohex-1-enyl)piperidine, -pyrrolidine, and -morpholine as an effi cient approach to 4,5,6,7-tetrahydroindoles


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Abstract

1-(Cyclohex-1-enyl)piperidine, -pyrrolidine, and -morpholine react with ethyl bromopyruvate in refluxing dioxane to afford the corresponding 4,5,6,7-tetrahydroindole derivatives. Possibility to convert the synthesized compounds into their aromatic counterparts was exemplified by one model compound.

About the authors

V. A. Mamedov

A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”; Kazan National Research Technological University

Author for correspondence.
Email: mamedov@iopc.ru
Russian Federation, 8 ul. Arbuzova, Kazan, 420088; 68 ul. Karl Marx, Kazan, 420015

A. I. Zamaletdinova

A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”; Kazan National Research Technological University

Email: mamedov@iopc.ru
Russian Federation, 8 ul. Arbuzova, Kazan, 420088; 68 ul. Karl Marx, Kazan, 420015

V. V. Syakaev

A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”

Email: mamedov@iopc.ru
Russian Federation, 8 ul. Arbuzova, Kazan, 420088

E. A. Khafizova

A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”

Email: mamedov@iopc.ru
Russian Federation, 8 ul. Arbuzova, Kazan, 420088

Sh. K. Latypov

A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”

Email: mamedov@iopc.ru
Russian Federation, 8 ul. Arbuzova, Kazan, 420088

O. G. Sinyashin

A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”; Kazan National Research Technological University

Email: mamedov@iopc.ru
Russian Federation, 8 ul. Arbuzova, Kazan, 420088; 68 ul. Karl Marx, Kazan, 420015

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