Lipase enzymatic microreactor in polysaccharide hydrogel: structure and properties
- Авторы: Bogdanova L.R.1, Rogov A.M.2, Zueva O.S.3, Zuev Y.F.1,2,3
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Учреждения:
- Kazan Institute of Biochemistry and Biophysics, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sceinces,”
- Kazan (Volga Region) Federal University
- Кazan State Power Engineering University
- Выпуск: Том 68, № 2 (2019)
- Страницы: 400-404
- Раздел: Full Articles
- URL: https://ogarev-online.ru/1066-5285/article/view/243260
- DOI: https://doi.org/10.1007/s11172-019-2399-1
- ID: 243260
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Аннотация
An enzymatic microreactor was designed on the basis of sodium alginate hydrogel containing a lipolytic enzyme (Candida rugosa lipase) in the polymer matrix pores. The functional properties of lipase were characterized in polysaccharide hydrogel of different concentrations. The polysaccharide hydrogel matrix was shown to act as a microreactor, where the enzyme retains activity during numerous catalytic cycles and allows designing long-acting drug systems of enzymatic nature.
Об авторах
L. Bogdanova
Kazan Institute of Biochemistry and Biophysics, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sceinces,”
Email: zuev@kibb.knc.ru
Россия, 2/13 ul. Lobachevskogo, Kazan, 420111
A. Rogov
Kazan (Volga Region) Federal University
Email: zuev@kibb.knc.ru
Россия, 18 ul. Kremlevskaya, Kazan, 420018
O. Zueva
Кazan State Power Engineering University
Email: zuev@kibb.knc.ru
Россия, 51 ul. Krasnoselskaya, Kazan, 420066
Yu. Zuev
Kazan Institute of Biochemistry and Biophysics, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sceinces,”; Kazan (Volga Region) Federal University; Кazan State Power Engineering University
Автор, ответственный за переписку.
Email: zuev@kibb.knc.ru
Россия, 2/13 ul. Lobachevskogo, Kazan, 420111; 18 ul. Kremlevskaya, Kazan, 420018; 51 ul. Krasnoselskaya, Kazan, 420066
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