Effect of Eluting the 99Mo/99mTc Generator More than Once in 24 h on the Efficiency of the 99mTc-MIBI Complex

Abstract

The effect of heating time, heating temperature, the amount of activity added to the MIBI kit, and the age of the formulated kit on the radiochemical purity of ^99mTc-MIBI complex is demonstrated. 1-mCi (37-MBq) ^99mTc-MIBI samples were prepared using the standard boiling water bath procedure. Qualitative and quantitative studies were done for the samples. The radiochemical purity of ^99mTc that had been eluted from two types of ⁹⁹Mo/^99mTc generators was studied. The efficiency of ^99mTc-MIBI samples was tested based on these studies. The results obtained show that eluting ⁹⁹Mo/^99mTc generators more than once in 24 h can lead to increased medical risks in patients with myocardial infarction.