Influence of temperature on the rhombic shape of paracetamol molecular crystals
- Autores: Belyaev A.P.1, Rubets V.P.2, Antipov V.V.1
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Afiliações:
- St. Petersburg State Chemical Pharmaceutical Academy
- St. Petersburg State Technological Institute
- Edição: Volume 62, Nº 4 (2017)
- Páginas: 645-647
- Seção: Short Communications
- URL: https://ogarev-online.ru/1063-7842/article/view/199314
- DOI: https://doi.org/10.1134/S1063784217040041
- ID: 199314
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Resumo
The method of differential scanning ellipsometry has been used to study the influence of heating on the rhombic shape of paracetamol molecular crystals. Rhombic molecular paracetamol crystals have been synthesized in vacuum from the vapor phase of paracetamol as a result of complex transformation, which includes a second-order transition that gives rise to a pretransition phase. It has been found that these crystals contain monoclinic nuclei, which favor the form I-to-form II polymorphic transformation during heating.
Sobre autores
A. Belyaev
St. Petersburg State Chemical Pharmaceutical Academy
Autor responsável pela correspondência
Email: Alexei.Belyaev@pharminnotech.com
Rússia, ul. Prof. Popova 14, St. Petersburg, 197376
V. Rubets
St. Petersburg State Technological Institute
Email: Alexei.Belyaev@pharminnotech.com
Rússia, Moskovskii pr. 26, St. Petersburg, 190013
V. Antipov
St. Petersburg State Chemical Pharmaceutical Academy
Email: Alexei.Belyaev@pharminnotech.com
Rússia, ul. Prof. Popova 14, St. Petersburg, 197376
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