FUNCTIONAL ACTIVITY OF NEUTROPHILS OF BLOOD OF RABBITS WITH SINGLE AND COMBINED STRESS IMPACT
- 作者: Kryachko O.V.1, Lukoyanova L.A.1, Taran A.M.1
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隶属关系:
- St. Petersburg State Academy of Veterinary Medicine
- 期: 卷 22, 编号 2-2 (2019)
- 页面: 825-827
- 栏目: ORIGINAL ARTICLES
- URL: https://ogarev-online.ru/1028-7221/article/view/119673
- DOI: https://doi.org/10.31857/S102872210006684-7
- ID: 119673
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详细
The purpose of this study is to study the effect of single and combined stress effects on the neutrophil function of the blood of rabbits in the experiment. For the experiment used 10 male rabbits, age ‒ 8 months, live weight 3,40±0,73 kg. In the first series of experiments, transport stress was modeled by transporting animals in a car. We caused immobilization stress in the second series of experiments by fixing the rabbit with its legs in the supine position. In the third series of experiments, a combination of effects was performed (immobilization, then, after three days, transportation). Phagocytic activity of blood neutrophils, phagocytic index, digestion index (killing) were determined. It was shown that the combination of stress effects negatively affects not only the phagocytic activity of neutrophils directly during their layering, but also the restoration of the functional systems of blood phagocytes in the post-stress period compared to single stresses.
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作者简介
O. Kryachko
St. Petersburg State Academy of Veterinary Medicine
编辑信件的主要联系方式.
Email: pathophys-spbgavm@yandex.ru
Dr., Prof., Head of the Department of Pathological Physiology,
St. Petersburg
俄罗斯联邦L. Lukoyanova
St. Petersburg State Academy of Veterinary Medicine
Email: fake@neicon.ru
Ph.D., Associate Professor, Department of Pathological Physiology,
St. Petersburg
俄罗斯联邦A. Taran
St. Petersburg State Academy of Veterinary Medicine
Email: fake@neicon.ru
graduate student of the Department of Pathological Physiology,
St. Petersburg
俄罗斯联邦参考
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- Baccan G. C., Sesti-Costa R., Chedraoui-Silva S., Mantovani B. Effects of cold stress, corticosterone and catecholamines on phagocytosis in mice: differences between resting and activated macrofhages// NeuroImmunoModulation. 2010. Т. 17. № 6. С. 379–385.
- Крячко О.В., Таран А. М. Сравнительная оценка влияния стрессов различной этиологии на окислительный статус нейтрофилов крови кроликов // Международный вестник ветеринарии. 2018. № 2. С. 91–95.
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